Retrospective Analysis of the Real-World Use of Topical Antimicrobials in the Paediatric Population with Impetigo in Italy: Focus on the Role of Ozenoxacin 1% Cream

被引：2

作者：

Barbieri, Elisa ^{[1
]}

Cavagnis, Sara ^{[2
]}

Boracchini, Riccardo ^{[3
,4
]}

Scamarcia, Antonio ^{[2
]}

Testa, Angela ^{[5
]}

Ciarniello, Maria Grazia ^{[5
]}

Martinelli, Biancangela ^{[5
]}

Cantarutti, Luigi ^{[2
]}

Giaquinto, Carlo ^{[1
,4
]}

Cantarutti, Anna ^{[3
,4
]}

机构：

[1] Univ Padua, Dept Woman & Child Hlth, Div Pediat Infect Dis, I-35128 Padua, Italy

[2] Soc Serv Telematici Pedianet, I-35100 Padua, Italy

[3] Univ Milano Bicocca, Dept Stat & Quantitat Methods, Unit Biostat Epidemiol & Publ Hlth, I-20126 Milan, Italy

[4] Univ Milano Bicocca, Natl Ctr Healthcare Res & Pharmacoepidemiol, Dept Stat & Quantitat Methods, I-20126 Milan, Italy

[5] Angelini Pharm SpA, I-00181 Rome, Italy

来源：

CHILDREN-BASEL | 2023年 / 10卷 / 03期

关键词：

topical antibiotics; children; impetigo; ozenoxacin; Pedianet database; Italy; RESISTANT STAPHYLOCOCCUS-AUREUS; FUSIDIC ACID;

D O I：

10.3390/children10030547

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Using electronic data from a large population-based network of Family Paediatricians (Pedianet), we aimed to describe the use of topical antimicrobials, including ozenoxacin 1% cream, in impetigo in children in Italy. We included 2929 children aged 6 months-14 years from 2016 to 2019 with at least one episode of impetigo treated with topical antimicrobials. Overall, 3051 cases of impetigo were included in the analysis. Treatment started in most cases on the same day as the impetigo diagnosis and lasted around eight days. In about 8% of the cases, a systemic antibiotic was prescribed after the topical antimicrobial, usually after 4-14 days. In this study, ozenoxacin was used in 8% of the cases. Treatment duration was significantly shorter for patients prescribed ozenoxacin compared to the whole study population (median of six vs. seven days, respectively). In contrast, the rate of treatment failure was similar. Very few adverse reactions were identified.

引用

页数：9

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