Fabrication and Characterization of Porous Diopside/Akermanite Ceramics with Prospective Tissue Engineering Applications

被引：3

作者：

Nicoara, Adrian Ionut ^{[1
,2
,3
]}

Alecu, Andrada Elena ^{[1
,3
]}

Balaceanu, Gabriel-Costin ^{[1
]}

Puscasu, Eliza Maria ^{[1
]}

Vasile, Bogdan Stefan ^{[3
,4
]}

Trusca, Roxana ^{[1
,3
]}

机构：

[1] Natl Univ Sci & Technol Politehn Bucharest, Fac Chem Engn & Biotechnol, Dept Sci & Engn Oxide Mat & Nanomat, Bucharest 011061, Romania

[2] Natl R&D Inst Nonferrous & Rare Met, IMNR, Bucharest, Romania

[3] Natl Univ Sci & Technol Politehn Bucharest, Natl Res Ctr Micro & Nanomat, Bucharest 060042, Romania

[4] Natl Univ Sci & Technol Politehn Bucharest, Res Ctr Adv Mat Prod & Proc, Bucharest 060042, Romania

来源：

MATERIALS | 2023年 / 16卷 / 16期

关键词：

porous ceramic; hard tissue; diopside; akermanite; bone regeneration; sucrose; MECHANICAL-PROPERTIES; BONE; SCAFFOLDS; BIOACTIVITY; PHOSPHATE;

D O I：

10.3390/ma16165548

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Tissue engineering requires new materials that can be used to replace damaged bone parts. Since hydroxyapatite, currently widely used, has low mechanical resistance, silicate ceramics can represent an alternative. The aim of this study was to obtain porous ceramics based on diopside (CaMgSi2O6) and akermanite (Ca2MgSi2O7) obtained at low sintering temperatures. The powder synthesized by the sol-gel method was pressed in the presence of a porogenic agent represented by commercial sucrose in order to create the desired porosity. The ceramic bodies obtained after sintering thermal treatment at 1050 degrees C and 1250 degrees C, respectively, were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR) to determine the chemical composition. The open porosity was situated between 32.5 and 34.6%, and the compressive strength had a maximum value of 11.4 MPa for the samples sintered at 1250 degrees C in the presence of a 20% wt porogenic agent. A cell viability above 70% and the rapid development of an apatitic phase layer make these materials good candidates for use in hard tissue engineering.

引用

页数：15