Frailty and Inflammatory Bowel Disease: A Scoping Review of Current Evidence

被引：7

作者：

Fons, Anne ^{[1
,2
]}

Kalisvaart, Kees ^{[2
]}

Maljaars, Jeroen ^{[1
]}

机构：

[1] Leiden Univ, Dept Gastroenterol & Hepatol, Med Ctr, NL-2333 ZA Leiden, Netherlands

[2] Spaarne Gasthuis, Dept Geriatr Med, NL-2035 RC Haarlem, Netherlands

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 02期

关键词：

inflammatory bowel disease; Crohn's disease; ulcerative colitis; frailty; elderly; geriatric assessment; OLDER-ADULTS; PREVALENCE; RISK; SARCOPENIA; ACCUMULATION; INFECTIONS; PHENOTYPE; OUTCOMES; INDEX; CALL;

D O I：

10.3390/jcm12020533

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Frailty is increasingly recognized as an important concept in patients with Inflammatory Bowel Disease (IBD). The aim of this scoping review is to summarize the current literature on frailty in IBD. We will discuss the definition of frailty, frailty assessment methods, the prevalence of frailty, risk factors for frailty and the prognostic value of frailty in IBD. A scoping literature search was performed using the PubMed database. Frailty prevalence varied from 6% to 53.9%, depending on the population and frailty assessment method. Frailty was associated with a range of adverse outcomes, including an increased risk for all-cause hospitalization and readmission, mortality in non-surgical setting, IBD-related hospitalization and readmission. Therefore, frailty assessment should become integrated as part of routine clinical care for older patients with IBD.

引用

页数：18

共 69 条

[31] Clinical frailty scale as a point of care prognostic indicator of mortality in COVID-19: a systematic review and meta-analysis [J].

Kastora, Stavroula ;

Kounidas, Georgios ;

Perrott, Sarah ;

Carter, Ben ;

Hewitt, Jonathan ;

Myint, Phyo Kyaw .

ECLINICALMEDICINE, 2021, 36

[32] Ageing well: a review of sarcopenia and frailty [J].

Keevil, Victoria L. ;

Romero-Ortuno, Roman .

PROCEEDINGS OF THE NUTRITION SOCIETY, 2015, 74 (04) :337-347

[33] What are the most effective interventions to improve physical performance in pre-frail and frail adults? A systematic review of randomised control trials [J].

Kidd, Tara ;

Mold, Freda ;

Jones, Claire ;

Ream, Emma ;

Grosvenor, Wendy ;

Sund-Levander, Martha ;

Tingstrom, Pia ;

Carey, Nicola .

BMC GERIATRICS, 2019, 19 (1)

[34] Systematic review of the utility of the frailty index and frailty phenotype to predict all-cause mortality in older people [J].

Kim, Dani J. ;

Massa, M. Sofia ;

Potter, Caroline M. ;

Clarke, Robert ;

Bennett, Derrick A. .

SYSTEMATIC REVIEWS, 2022, 11 (01)

[35] Prevalence and Implications of Frailty in Older Adults With Incident Inflammatory Bowel Diseases: A Nationwide Cohort Study [J].

Kochar, Bharati ;

Jylhava, Juulia ;

Soderling, Jonas ;

Ritchie, Christine S. ;

Group, Swibreg Study ;

Ludvigsson, Jonas F. ;

Khalili, Hamed ;

Olen, Ola .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2022, 20 (10) :2358-+

[36] Frailty in inflammatory bowel diseases: an emerging concept [J].

Kochar, Bharati ;

Orkaby, Ariela R. ;

Ananthakrishnan, Ashwin N. ;

Ritchie, Christine S. .

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2021, 14

[37] Frailty is independently associated with mortality in 11 001 patients with inflammatory bowel diseases [J].

Kochar, Bharati ;

Cai, Winston ;

Cagan, Andrew ;

Ananthakrishnan, Ashwin N. .

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2020, 52 (02) :311-318

[38] Pretreatment Frailty Is Independently Associated With Increased Risk of Infections After Immunosuppression in Patients With In flammatory Bowel Diseases [J].

Kochar, Bharati ;

Cai, Winston ;

Cagan, Andrew ;

Ananthakrishnan, Ashwin N. .

GASTROENTEROLOGY, 2020, 158 (08) :2104-+

[39] Inflammatory Bowel Disease Patients Who Respond to Treatment with Anti-tumor Necrosis Factor Agents Demonstrate Improvement in Pre-treatment Frailty [J].

Kochar, Bharati D. ;

Cai, Winston ;

Ananthakrishnan, Ashwin N. .

DIGESTIVE DISEASES AND SCIENCES, 2022, 67 (02) :622-628

[40] Adjusted Chemotherapy According to Frailty Status in Elderly Patients With Diffuse Large B-Cell Lymphoma: Experience From a Single Referral Center in Mexico City [J].

Lastra-German, Isabel K. ;

Navarrete-Reyes, Ana P. ;

Mejia-Dominguez, Nancy R. ;

Agreda-Vasquez, Gladys P. .

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2019, 19 (02) :E98-E106

← 1 2 3 4 5 6 7 →