Plasma Transforming Growth Factor-β1 (TGF-β1) Levels Increase with Age and Aortic Stenosis Progression and Low-Dose Galunisertib Attenuates Disease Progression in Mice

被引：0
作者：
Subramani, Kumar [1 ]
Varshney, Rohan [1 ]
Subramanian, Sandeep [1 ]
Bander, Jeffrey [2 ]
Babii, Denys [1 ]
Ahamed, Jasimuddin [1 ]
机构：
[1] Oklahoma Med Res Fdn, Oklahoma City, OK USA
[2] Mt Sinai Sch Med, New York, NY USA
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-186944
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Transforming Growth Factor-β1/Smad Signaling in Glomerulonephritis and Its Association with Progression to Chronic Kidney Disease
    Chalkia, Aglaia
    Gakiopoulou, Harikleia
    Theohari, Irini
    Foukas, Periklis G.
    Vassilopoulos, Dimitrios
    Petras, Dimitrios
    AMERICAN JOURNAL OF NEPHROLOGY, 2021, 52 (08) : 653 - 665
  • [32] Urine but not plasma transforming growth factor-β1 (TGF-β1) is increased in conjunction with altered renal immunolocalization in experimental diabetes mellitus
    Lane, PH
    Babushkina-Patz, N
    PEDIATRIC RESEARCH, 1999, 45 (04) : 334A - 334A
  • [33] Urine but Not Plasma Transforming Growth Factor-β1 (TGF-β1) Is Increased in Conjunction with Altered Renal Immunolocalization in Experimental Diabetes Mellitus
    Pascale H Lane
    Nataliy Babushkina-Patz
    Pediatric Research, 1999, 45 : 334 - 334
  • [34] Early postoperative plasma transforming growth factor-β1 is a strong predictor of biochemical progression after radical prostatectomy
    Shariat, Shahrokh F.
    Walz, Jochen
    Roehrborn, Claus G.
    Montorsi, Francesco
    Jeldres, Claudio
    Saad, Fred
    Karakiewicz, Pierre I.
    JOURNAL OF UROLOGY, 2008, 179 (04) : 1593 - 1597
  • [35] Transforming growth factor-β1 (TGF-β1)-induced myocardial fibrosis is associated with an inhibition of interstitial collagenase (MMP) activity in transgenic mice
    Seeland, U
    Haeuseler, C
    Hinrichs, R
    Pfitzner, T
    Scharffetter-Kochanek, K
    CIRCULATION, 2001, 104 (17) : 187 - 187
  • [36] High levels of transforming growth factor beta 1 in patients with colorectal cancer: Association with disease progression
    Tsushima, H
    Kawata, S
    Tamura, S
    Ito, N
    Shirai, Y
    Kiso, S
    Imai, Y
    Shimomukai, H
    Nomura, Y
    Matsuda, Y
    Matsuzawa, Y
    GASTROENTEROLOGY, 1996, 110 (02) : 375 - 382
  • [37] Suppression of latent transforming growth factor-β (TGF-β)-binding protein 1 (LTBP1) inhibits natural killer/T cell lymphoma progression by inactivating the TGF-β/Smad and p38MAPK pathways
    Lin, Rui
    Li, Xiaoli
    Wu, Shaoxuan
    Qian, Siyu
    Hou, Huting
    Dong, Meng
    Zhang, Xudong
    Zhang, Mingzhi
    EXPERIMENTAL CELL RESEARCH, 2021, 407 (01)
  • [38] Levels of serum transforming growth factor-β1 do not increase in Behcet's disease, in contrast to rheumatoid arthritis
    Eksioglu-Demiralp, E
    Direskeneli, H
    Akoglu, T
    JOURNAL OF RHEUMATOLOGY, 1999, 26 (04) : 1010 - 1011
  • [39] Retinoic acid induced repair in the lung of adult hyperoxic mice, reducing transforming growth factor-β1 (TGF-β1) mediated abnormal alterations
    Kayalar, Ozgecan
    Oztay, Fusun
    ACTA HISTOCHEMICA, 2014, 116 (05) : 810 - 819
  • [40] Age-related changes in the response of human articular cartilage to IL-1α and transforming growth factor-β (TGF-β) -: Chondrocytes exhibit a diminished sensitivity to TGF-β
    Hickery, MS
    Bayliss, MT
    Dudhia, J
    Lewthwaite, JC
    Edwards, JCW
    Pitsillides, AA
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (52) : 53063 - 53071
12345