[1] Univ Porto, i3S Inst Res & Innovat Hlth, Porto, Portugal
[2] Univ Porto, ICBAS Inst Biomed Sci Abel Salazar, Porto, Portugal
[3] Katholieke Univ Leuven, Dept Cellular & Mol Med, Leuven, Belgium
[4] Univ Copenhagen, Novo Nordisk Fdn Ctr Prot Res, Copenhagen, Denmark
[5] Univ Dundee, Sch Med, Dundee, Scotland