Laser-induced porous graphene electrodes from polyketimine membranes for paracetamol sensing

被引：16

作者：

Baachaoui, Sabrine ^{[1
]}

Mabrouk, Walid ^{[2
]}

Charradi, Khaled ^{[3
]}

Slimi, Bechir ^{[3
]}

Ramadan, Ahmed M. ^{[4
]}

Elsamra, Rehab M. I. ^{[4
]}

Alhussein, Akram ^{[5
]}

Keshk, Sherif M. A. S. ^{[6
]}

Raouafi, Noureddine ^{[1
]}

机构：

[1] Univ Tunis El Manar, Fac Sci, Dept Chem, Campus Univ Tunis El Manar, Tunis 2092, Tunisia

[2] Water Res & Technol Ctr, Lab Water Membranes & Biotechnol Environm, Technopk Borj Cedria, Soliman 8020, Tunisia

[3] Res & Technol Ctr Energy, Nanomat & Syst Renewable Energy Lab, Technopk Borj Cedria, Soliman 8020, Tunisia

[4] Alexandria Univ, Fac Sci, Dept Chem, POB 426, Alexandria 21321, Egypt

[5] Univ Technol Troyes, Technol Pole South Champagne, Lavoisier Rd, F-52800 Nogent, France

[6] Become Technol Sci & Automat Lab, 63 Rue Tolbiac, F-75013 Paris, France

来源：

ROYAL SOCIETY OPEN SCIENCE | 2023年 / 10卷 / 08期

关键词：

polyketimine; membrane; laser-induced electrode; sensing; paracetamol; health; SENSOR; ACETAMINOPHEN; NANOPARTICLES; REVERSIBILITY; HYDROQUINONE; VOLTAMMETRY; INJECTION; DOPAMINE; ACID; DRUG;

D O I：

10.1098/rsos.230294

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The development of cost-effective materials for fabricating electrodes is crucial for drug, pharmaceutical and environmental applications. This paper presents the synthesis and characterization of a novel polyketimine (PKI) membrane obtained by condensing partially of different weight percentages of oxidized polyvinyl alcohol and aminated polyether sulfone. Using the PKI membrane as a scaffold, we introduced laser-induced graphene electrodes (LIGEs) for the efficient electrochemical sensing of paracetamol (PCM), which serves as a model drug. Electrochemical measurements were conducted to assess the physico-chemical properties, including laser-induced porous graphene features, such as the heterogeneous electron transfer (HET) rate and electrochemically active surface area (ECSA). The obtained results demonstrate that the LIGEs exhibit excellent performance in PCM sensing, showing a linear detection range of 50-600 & mu;M with a detection limit (LOD) as low as 14.3 & mu;M and a good selectivity toward uric acid. Furthermore, the functionalization of the electrode surface with AuNPs improved the electrode physico-chemical properties (HET and ECSA) and lowered the detection limit down to 1.1 & mu;M. Consequently, these affordable electrodes hold great potential for analysing other drugs and detecting heavy metal cations in various applications.

引用

页数：14