The effect of therapeutic plasma exchange therapy on veno-venous ECMO weaning success in severe COVID-19 ARDS patients

被引：0

作者：

Aslan, Murat ^{[1
]}

Yilmaz, Rabia ^{[1
]}

Dogan, Murat ^{[1
]}

Cukurova, Zafer ^{[1
]}

机构：

[1] Univ Hlth Sci Bakirkoy Dr Sadi Konuk Training & R, Meltem St,Gol Plus Houses,29 Kucukcekmece, Istanbul, Turkiye

来源：

THERAPEUTIC APHERESIS AND DIALYSIS | 2023年 / 27卷 / 04期

关键词：

COVID-19; ECMO; plasma; therapeutic; weaning; EXTRACORPOREAL MEMBRANE-OXYGENATION; ORGANIZATION; SURVIVAL;

D O I：

10.1111/1744-9987.13979

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction Primarily, this study aimed to investigate the effect of TPE (therapeutic plasma exchange) treatment on successful ECMO weaning in severe COVID-19 ARDS patients treated with V-V ECMO.Methods The study was applied retrospectively on patients over the age of 18 who were hospitalized in the ICU between January 1, 2020 and March 1, 2022.Results The study was performed on 33 patients, 36.3% (n: 12) of whom received TPE treatment. The rate of successful ECMO weaning was statistically higher in the TPE treatment group (without TPE: 14.3% [n: 3], with TPE: 50% [n: 6], p = 0.044). The 1-month mortality was also statistically lower in the TPE treatment group (p = 0.044). In the logistic analysis, It was found that the risk of unsuccessful ECMO weaning increased 6 times in those who did not receive TPE treatment (OR; 6.0, 95% CI; 1.134-31.735, p = 0.035).Conclusion TPE treatment may increase the success rate of V-V ECMO weaning in severe COVID-19 ARDS patients treated with V-V ECMO.

引用

收藏

页码：780 / 789

页数：10

相关论文

共 37 条

[11] Poor survival with extracorporeal membrane oxygenation in acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19): Pooled analysis of early reports [J].

Henry, Brandon Michael ;

Lippi, Giuseppe .

JOURNAL OF CRITICAL CARE, 2020, 58 :27-28

[12] Comparison of mortality prediction models in acute respiratory distress syndrome undergoing extracorporeal membrane oxygenation and development of a novel prediction score: the PREdiction of Survival on ECMO Therapy-Score (PRESET-Score) [J].

Hilder, Michael ;

Herbstreit, Frank ;

Adamzik, Michael ;

Beiderlinden, Martin ;

Buerschen, Markus ;

Peters, Juergen ;

Frey, Ulrich H. .

CRITICAL CARE, 2017, 21

[13] Venovenous extracorporeal membrane oxygenation in adult respiratory failure: Scores for mortality prediction [J].

Hsin, Chun-Hsien ;

Wu, Meng-Yu ;

Huang, Chung-Chi ;

Kao, Kuo-Chin ;

Lin, Pyng-Jing .

MEDICINE, 2016, 95 (25)

[14] Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic [J].

Karagiannidis, Christian ;

Slutsky, Arthur S. ;

Bein, Thomas ;

Windisch, Wolfram ;

Weber-Carstens, Steffen ;

Brodie, Daniel .

CRITICAL CARE, 2021, 25 (01)

[15] The therapeutic efficacy of adjunct therapeutic plasma exchange for septic shock with multiple organ failure: a single-center experience [J].

Keith, Philip D. ;

Wells, Adam H. ;

Hodges, Jeremy ;

Fast, Stephen H. ;

Adams, Amber ;

Scott, L. Keith .

CRITICAL CARE, 2020, 24 (01)

[16] Therapeutic plasma exchange in adults with severe COVID-19 infection [J].

Khamis, Faryal ;

Al-Zakwani, Ibrahim ;

Al Hashmi, Sabria ;

Al Dowaiki, Samata ;

Al Bahrani, Maher ;

Pandak, Nenad ;

Al Khalili, Huda ;

Memish, Ziad .

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2020, 99 :214-218

[17] Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers [J].

Knaup, Hannah ;

Stahl, Klaus ;

Schmidt, Bernhard M. W. ;

Idowu, Temitayo O. ;

Busch, Markus ;

Wiesner, Olaf ;

Welte, Tobias ;

Haller, Hermann ;

Kielstein, Jan T. ;

Hoeper, Marius M. ;

David, Sascha .

CRITICAL CARE, 2018, 22

[18]

Lebreton G, 2021, LANCET RESP MED, V9, pE62, DOI [10.1016/S2213-2600(21)00280-0, 10.1016/S2213-2600(21)00096-5]

[19] Critically ill patients with COVID-19 with ECMO and artificial liver plasma exchange A retrospective study [J].

Liu, Jian ;

Dong, Yong-Quan ;

Yin, Jie ;

He, Guojun ;

Wu, Xiaoxin ;

Li, Jianping ;

Qiu, Yunqing ;

He, Xuelin .

MEDICINE, 2020, 99 (26) :E21012

[20] Biomarkers and outcomes of COVID-19 hospitalisations: systematic review and meta-analysis [J].

Malik, Preeti ;

Patel, Urvish ;

Mehta, Deep ;

Patel, Nidhi ;

Kelkar, Raveena ;

Akrmah, Muhammad ;

Gabrilove, Janice L. ;

Sacks, Henry .

BMJ EVIDENCE-BASED MEDICINE, 2021, 26 (03) :107-+

← 1 2 3 4 →