Synthesis of benzothiazole and benzimidazole derivatives via an eco-friendly method using piperazine immobilized on nano-ZnO-sulfuric acid as a powerful catalyst

被引：8

作者：

Mousapour, Maryam ^{[1
]}

Shirini, Farhad ^{[1
]}

机构：

[1] Univ Guilan, Coll Sci, Dept Chem, Rasht 4133519141, Iran

来源：

JOURNAL OF NANOSTRUCTURE IN CHEMISTRY | 2023年 / 13卷 / 04期

关键词：

ZnO NPs; Piperazine; Immobilized ionic liquids; Multi-component reactions; Pyrimido[1,2-a]benzimidazole; 1-(Benzothiazolylamino) phenylmethyl-2-naphthol; ONE-POT SYNTHESIS; IONIC-LIQUID; EFFICIENT CATALYST; 3-COMPONENT SYNTHESIS; 2-AMINOBENZOTHIAZOLOMETHYL NAPHTHOLS; MULTICOMPONENT SYNTHESIS; GREEN SYNTHESIS; SOLVENT; SILICA; WATER;

D O I：

10.1007/s40097-021-00450-5

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this research, the synthesis of piperazine immobilized on nano-ZnO-sulfuric acid (PINZS) as a new piperazine-based nano-reagent is reported. After identification of PINZS using different techniques including XRD (X-ray powder diffraction), TGA (thermogravimetric analysis), FT-IR (Fourier transform infrared spectroscopy), FESEM (field emission scanning electron microscopy), and EDX (energy-dispersive X-ray) analysis, this reagent is efficiently used for the synthesis of 1-(benzothiazolylamino) phenylmethyl-2-naphthols and pyrimido[1, 2-a]benzimidazoles via a domino Knoevenagel/Michael sequence which identified acceptable reaction times (7-45 min.), great yields (up to 98%) and ease of the preparation, separation, and recovery of PINZS (for three times) as the most important features of this protocol. [GRAPHICS] .

引用

页码：405 / 422

页数：18