Synthesis of benzothiazole and benzimidazole derivatives via an eco-friendly method using piperazine immobilized on nano-ZnO-sulfuric acid as a powerful catalyst

被引：8
|
作者：
Mousapour, Maryam [1 ]
Shirini, Farhad [1 ]
机构：
[1] Univ Guilan, Coll Sci, Dept Chem, Rasht 4133519141, Iran
来源：
JOURNAL OF NANOSTRUCTURE IN CHEMISTRY | 2023年 / 13卷 / 04期
关键词：
ZnO NPs; Piperazine; Immobilized ionic liquids; Multi-component reactions; Pyrimido[1,2-a]benzimidazole; 1-(Benzothiazolylamino) phenylmethyl-2-naphthol; ONE-POT SYNTHESIS; IONIC-LIQUID; EFFICIENT CATALYST; 3-COMPONENT SYNTHESIS; 2-AMINOBENZOTHIAZOLOMETHYL NAPHTHOLS; MULTICOMPONENT SYNTHESIS; GREEN SYNTHESIS; SOLVENT; SILICA; WATER;
D O I：
10.1007/s40097-021-00450-5
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this research, the synthesis of piperazine immobilized on nano-ZnO-sulfuric acid (PINZS) as a new piperazine-based nano-reagent is reported. After identification of PINZS using different techniques including XRD (X-ray powder diffraction), TGA (thermogravimetric analysis), FT-IR (Fourier transform infrared spectroscopy), FESEM (field emission scanning electron microscopy), and EDX (energy-dispersive X-ray) analysis, this reagent is efficiently used for the synthesis of 1-(benzothiazolylamino) phenylmethyl-2-naphthols and pyrimido[1, 2-a]benzimidazoles via a domino Knoevenagel/Michael sequence which identified acceptable reaction times (7-45 min.), great yields (up to 98%) and ease of the preparation, separation, and recovery of PINZS (for three times) as the most important features of this protocol. [GRAPHICS] .
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页码：405 / 422
页数：18
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