Quantifying Ligand Binding to the Surface of Metal-Organic Frameworks

被引：13

作者：

Wang, Austin ^{[1
]}

Barcus, Kyle ^{[1
]}

Cohen, Seth M. ^{[1
]}

机构：

[1] Univ Calif, Dept Chem, Biochem, San Diego, La Jolla, CA 92093 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2023年 / 145卷 / 30期

基金：

美国国家科学基金会;

关键词：

SIZE;

D O I：

10.1021/jacs.3c04892

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The binding of molecules to the exterior surface of metal-organicframeworks (MOFs) is not a well-understood phenomenon. Herein, thesurface chemistry of three MOFs, UiO-66, MIL-88B-NH2, andZIF-8, is investigated using dye-displacement experiments. MOF particlesurfaces were modified with ligand-appended BODIPY dyes. The abilityof the coordinated dyes to be displaced by a variety of exogenousligands was measured by ultraviolet-visible spectroscopy. This methodallowed for measurement of apparent binding constants for differentligands to the MOF surface. As might be expected, ligand affinitywas dependent on the nature of the underlying metal-ligandcomposition of the MOF. This work provides a quantitative evaluationof ligand binding to MOF surfaces and important insights for the modulation,modification, and manipulation of MOFs.

引用

页码：16821 / 16827

页数：7

共 22 条

[1]

Avci C, 2018, NAT CHEM, V10, P78, DOI [10.1038/NCHEM.2875, 10.1038/nchem.2875]

[2] Immobilization of myoglobin on phosphate and phosphonate grafted-zirconia nanoparticles [J].

Bellezza, F ;

Cipiciani, A ;

Quotadamo, MA .

LANGMUIR, 2005, 21 (24) :11099-11104

[3] Formulation of Metal-Organic Framework-Based Drug Carriers by Controlled Coordination of Methoxy PEG Phosphate: Boosting Colloidal Stability and Redispersibility [J].

Chen, Xu ;

Zhuang, Yunhui ;

Rampal, Nakul ;

Hewitt, Rachel ;

Divitini, Giorgio ;

O'Keefe, Christopher A. ;

Liu, Xiewen ;

Whitaker, Daniel J. ;

Wills, John W. ;

Jugdaohsingh, Ravin ;

Powell, Jonathan J. ;

Yu, Han ;

Grey, Clare P. ;

Scherman, Oren A. ;

Fairen-Jimenez, David .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 143 (34) :13557-13572

[4] An efficient synthesis of a 6"-BODIPY-α-Galactosylceramide probe for monitoring α-Galactosylceramide uptake by cells [J].

Cheng, Janice M. H. ;

Chee, Stephanie H. ;

Dolen, Yusuf ;

Verdoes, Martijn ;

Timmer, Mattie S. M. ;

Stocker, Bridget L. .

CARBOHYDRATE RESEARCH, 2019, 486

[5] Ligand Exchange in the Synthesis of Metal-Organic Frameworks Occurs Through Acid-Catalyzed Associative Substitution [J].

Chiu, Chih-Chiang ;

Shieh, Fa-Kuen ;

Tsai, Hui-Hsu Gavin .

INORGANIC CHEMISTRY, 2019, 58 (21) :14457-14466

[6]

Desai AV., 2023, ACS APPL MATER INTER, V15, P9058, DOI [10.1021/acsami.2c21187, DOI 10.1021/ACSAMI.2C21187]

[7] Coordinatively Immobilized Monolayers on Porous Coordination Polymer Crystals [J].

Kondo, Mio ;

Furukawa, Shuhei ;

Hirai, Kenji ;

Kitagawa, Susumu .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (31) :5327-5330

[8] Selective Surface PEGylation of UiO-66 Nanoparticles for Enhanced Stability, Cell Uptake, and pH-Responsive Drug Delivery [J].

Lazaro, Isabel Abanades ;

Haddad, Salame ;

Sacca, Sabrina ;

Orellana-Tavra, Claudia ;

Fairen-Jimenez, David ;

Forgan, Ross S. .

CHEM, 2017, 2 (04) :561-578

[9] Active Role of Methanol in Post-Synthetic Linker Exchange in the Metal-Organic Framework UiO-66 [J].

Marreiros, Joao ;

Caratelli, Chiara ;

Hajek, Julianna ;

Krajnc, Andraz ;

Fleury, Guillaume ;

Bueken, Bart ;

De Vos, Dirk E. ;

Mali, Gregor ;

Roeffaers, Maarten B. J. ;

Van Speybroeck, Veronique ;

Ameloot, Rob .

CHEMISTRY OF MATERIALS, 2019, 31 (04) :1359-1369

[10] Novel Route to Size-Controlled Fe-MIL-88B-NH2 Metal-Organic Framework Nanocrystals [J].

Minh-Hao Pham ;

Gia-Thanh Vuong ;

Anh-Tuan Vu ;

Trong-On Do .

LANGMUIR, 2011, 27 (24) :15261-15267

← 1 2 3 →