Magnetic resonance imaging modalities aid in the differential diagnosis of atypical parkinsonian syndromes

被引:2
作者
Tinaz, Sule [1 ,2 ]
机构
[1] Yale Sch Med, Dept Neurol, Div Movement Disorders, New Haven, CT 06510 USA
[2] Yale Sch Med, Clin Neurosci Imaging Ctr, Dept Neurol, New Haven, CT 06510 USA
来源
FRONTIERS IN NEUROLOGY | 2023年 / 14卷
关键词
atypical parkinsonism; magnetic resonance parkinsonism index; neuromelanin MRI; diffusion MRI; susceptibility-weighted imaging; quantitative susceptibility mapping; PROGRESSIVE SUPRANUCLEAR PALSY; SUBSTANTIA-NIGRA; DISEASE; IRON; MRI; NEUROMELANIN; MULTICENTER; BIOMARKERS; INDEX;
D O I
10.3389/fneur.2023.1082060
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Accurate and timely diagnosis of atypical parkinsonian syndromes (APS) remains a challenge. Especially early in the disease course, the clinical manifestations of the APS overlap with each other and with those of idiopathic Parkinson's disease (PD). Recent advances in magnetic resonance imaging (MRI) technology have introduced promising imaging modalities to aid in the diagnosis of APS. Some of these MRI modalities are also included in the updated diagnostic criteria of APS. Importantly, MRI is safe for repeated use and more affordable and accessible compared to nuclear imaging. These advantages make MRI tools more appealing for diagnostic purposes. As the MRI field continues to advance, the diagnostic use of these techniques in APS, alone or in combination, are expected to become commonplace in clinical practice.
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页数:7
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