Transgenerational epigenetic control of constitutive heterochromatin, transposons, and centromeres

被引:4
作者
Fukagawa, Tatsuo [1 ]
Kakutani, Tetsuji [2 ]
机构
[1] Osaka Univ, Grad Sch Frontier Biosci, Suita, Osaka 5650871, Japan
[2] Univ Tokyo, Dept Biol Sci, Hongo 7-3-1,Bunkyo Ku, Tokyo 1130033, Japan
基金
日本科学技术振兴机构;
关键词
DNA METHYLATION; CENP-A; ARABIDOPSIS-THALIANA; STABLE INHERITANCE; KINETOCHORE; CHROMATIN; MAINTENANCE; NUCLEOSOME; MUTATION; GENE;
D O I
10.1016/j.gde.2023.102021
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Epigenetic mechanisms are important not only for development but also for genome stability and chromosome dynamics. The latter types of epigenetic controls can often be transgenerational. Here, we review recent progress in two examples of transgenerational epigenetic control: i) the control of constitutive heterochromatin and transposable elements and ii) epigenetic mechanisms that regulate centromere specification and functions. We also discuss the biological significance of enigmatic associations among centromeres, transposons, and constitutive heterochromatin.
引用
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页数:14
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