Predictive accuracy of years score in diagnosis of pulmonary embolism

被引:1
作者
Fayiad, Hussien [1 ]
Moussa, Heba [1 ]
Nosair, Yara [1 ]
Mostafa, Amira Ismail [1 ]
机构
[1] Cairo Univ, Fac Med, Dept Chest Dis, Kasr Alainy, Cairo, Egypt
关键词
YEARS score; Pulmonary embolism; D-dimer;
D O I
10.1186/s43168-024-00269-y
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background Pulmonary embolism (PE) is a sudden obstruction of pulmonary arteries usually associated with a high rate of mortality due to acute right ventricular failure. Early diagnosis is of much importance because most patients die within the first hours of presentation. Emergency management is usually highly valuable and right heart failure is potentially reversible. Multidetector computed tomography pulmonary angiography (CTPA) is the best diagnostic imaging modality to document acute pulmonary embolism. Overuse of CTPA increases the unrequired risk of radiation exposure, increasing the risk of malignancy, contrast-related anaphylaxis, and acute kidney injury. To abolish these issues, the simplified score for suspected acute pulmonary embolism using variable D dimer cut-off value in combination with clinical signs can exclude pulmonary embolism safely. Aim of the study To evaluate the predictive accuracy of YEARS score in the diagnosis of pulmonary embolism compared to CTPA that might lead to a decrease in the overuse of CTPA. Methods The study was held at the chest unit in Kasr ElAini hospitals. It included 50 patients, for which full history, examination, calculation of wells score, D-dimer, YEARS score, and CTPA were done. Results The results showed that the YEARS score succeeded in predicting the presence or the absence of PE in 80% of the 50 enrolled patients in our study. YEARS score has a sensitivity of 90% and specificity of 65%. Conclusion Patients with zero YEARS score and D-dimer >= 1000 ng/ml as well as those with >= 1 YEARS score and D-dimer >= 500 ng/ml are rendered PE likely by the YEARS algorithm with a sensitivity of 90%. Using years score, we can exclude pulmonary embolism in patients with zero YEARS score and a D-dimer. 1000 ng/ml as well as in patients with >= 1 YEARS score and D-dimer. 500 ng/ml with 65% specificity, thus decreasing overuse of CTPA in the diagnosis of PE.
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共 25 条
  • [1] Current Concepts: Acute Pulmonary Embolism.
    Agnelli, Giancarlo
    Becattini, Cecilia
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (03) : 266 - 274
  • [2] Ali IE., 2019, Minia J Med Res, V30, P17, DOI [10.21608/mjmr.2022.221976, DOI 10.21608/MJMR.2022.221976]
  • [3] YEARS Algorithm Versus Wells' Score: Predictive Accuracies in Pulmonary Embolism Based on the Gold Standard CT Pulmonary Angiography*
    Alkhatip, Ahmed Abdelaal Ahmed Mahmoud M.
    Donnelly, Maria
    Snyman, Lindi
    Conroy, Patrick
    Hamza, Mohamed Khaled
    Murphy, Ian
    Purcell, Andrew
    McGuire, David
    [J]. CRITICAL CARE MEDICINE, 2020, 48 (05) : 704 - 708
  • [4] Pulmonary embolism: epidemiological data and diagnosis in Kinshasa hospitals
    Bakebe, A.
    Kashongwe, I.
    Mulenga, C.
    Tshiasuma, M.
    Kabengele, B.
    Bisuta, S. F.
    Makulo, J. R.
    Kashongwe, Z.
    Kayembe, J-M.
    [J]. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 2017, 21 (08) : 875 - 879
  • [5] Current and Former Smoking and Risk for Venous Thromboembolism: A Systematic Review and Meta-Analysis
    Cheng, Yun-Jiu
    Liu, Zhi-Hao
    Yao, Feng-Juan
    Zeng, Wu-Tao
    Zheng, Dong-Dan
    Dong, Yu-Gang
    Wu, Su-Hua
    [J]. PLOS MEDICINE, 2013, 10 (09)
  • [6] External validation of the YEARS diagnostic algorithm for suspected pulmonary embolism
    Eddy, Maggie
    Robert-Ebadi, Helia
    Richardson, Lydia
    Bellesini, Marta
    Verschuren, Frank
    Moumneh, Thomas
    Meyer, Guy
    Righini, Marc
    Le Gal, Gregoire
    [J]. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2020, 18 (12) : 3289 - 3295
  • [7] Non-traumatic thoracic emergencies: CT diagnosis of acute pulmonary embolism: the first 10 years
    Ghaye, B
    Remy, J
    Remy-Jardin, M
    [J]. EUROPEAN RADIOLOGY, 2002, 12 (08) : 1886 - 1905
  • [8] Multicenter Evaluation of the YEARS Criteria in Emergency Department Patients Evaluated for Pulmonary Embolism
    Kabrhel, Christopher
    Vlieg, Astrid Van Hylckama
    Muzikanski, Alona
    Singer, Adam
    Fermann, Gregory J.
    Francis, Samuel
    Limkakeng, Alex
    Chang, Ann Marie
    Giordano, Nicholas
    Parry, Blair
    [J]. ACADEMIC EMERGENCY MEDICINE, 2018, 25 (09) : 987 - 994
  • [9] Trends in thrombolytic treatment and outcomes of acute pulmonary embolism in Germany
    Keller, Karsten
    Hobohm, Lukas
    Ebner, Matthias
    Kresoja, Karl-Patrik
    Muenzel, Thomas
    Konstantinides, Stavros, V
    Lankeit, Mareike
    [J]. EUROPEAN HEART JOURNAL, 2020, 41 (04) : 522 - 529
  • [10] Venous thromboembolism and prognosis in cancer
    Khorana, Alok A.
    [J]. THROMBOSIS RESEARCH, 2010, 125 (06) : 490 - 493