Neutrophil/Lymphocyte and Platelet/Lymphocyte Ratio in Preterm Premature Rupture of Membranes

被引:9
作者
Esercan, Alev [1 ]
Demir, Ismail [1 ]
机构
[1] Sanliurfa Educ & Res Hosp, Obstet & Gynecol, Sanliurfa, Turkiye
关键词
preterm birth; preterm premature rupture of membranes; platelet lymphocyte ratio; neutrophillymphocyte ratio; inflammation;
D O I
10.7759/cureus.38664
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aim: This study aimed to investigate maternal hematological laboratory parameters of pregnancies complicated with preterm premature rupture of membranes (PPROM) compared to mothers of healthy-term infants (control group). Materials and methods: This case-control study included 158 mothers who were divided into PPROM (n=67) and control (n=91) groups, respectively. Laboratory parameters of platelet, lymphocyte, and neutrophil counts, neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR) were recorded at the time of diagnosis for the PPROM group and at the time of hospital admission for birth for the control group. Results: NLR was significantly higher in the PPROM group than in the control group (p=0.001). The cutoff value of NLR to predict PPROM was 6.73 (AUC=0.671, 95% confidence interval=0.58-0.75, p=0.000). Conclusion: A cheap and routine NLR blood test can be used to predict PPROM before labor.
引用
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页数:5
相关论文
共 20 条
[11]   How do platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio change in women with preterm premature rupture of membranes, and threaten preterm labour? [J].
Ozel, Aysegul ;
Davutoglu, Ebru Alici ;
Yurtkal, Aslihan ;
Madazli, Riza .
JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2020, 40 (02) :195-199
[12]   Immune biomarkers in maternal plasma to identify histologic chorioamnionitis in women with preterm labor [J].
Park, Jeong Woo ;
Park, Kyo Hoon ;
Kook, Song Yi ;
Jung, Young Mi ;
Kim, Yu Mi .
ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2019, 299 (03) :725-732
[13]   The impact of residual oligohydramnios following preterm premature rupture of membranes on adverse pregnancy outcomes: a meta-analysis [J].
Pergialiotis, Vasilios ;
Bellos, Ioannis ;
Fanaki, Maria ;
Antsaklis, Aris ;
Loutradis, Dimitrios ;
Daskalakis, George .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2020, 222 (06) :628-630
[14]   Neutrophils to Lymphocyte Ratio: Earliest and Efficacious Markers of Sepsis [J].
Rehman, Fazal U. ;
Khan, Asadullah ;
Aziz, Adil ;
Iqbal, Madiha ;
Mahmood, Saad bin Zafar ;
Ali, Naureen .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (10)
[15]   Non-invasive prediction of histologic chorioamnionitis using maternal serum markers in women with preterm prelabour rupture of membranes [J].
Shi, Haoning ;
Sun, Lingling ;
Wang, Zhenjie ;
Zhang, Aimei ;
Cao, Huaiming ;
Zhao, Wanying ;
Wang, Hongyu ;
Yang, Xiao ;
Li, Jing .
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2022, 88 (03)
[16]  
Toprak E, 2017, J TURK-GER GYNECOL A, V18, P122, DOI 10.4274/jtgga.2017.0028
[17]   Association of subclinical markers of inflammation with preterm premature rupture of membranes and adverse neonatal results: a case control study [J].
Uckan, Kazim ;
Baskiran, Yusuf ;
Celegen, Izzet .
ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2022, 306 (06) :2063-2068
[18]   Platelet-to-Lymphocyte and Neutrophil-to-Lymphocyte Ratio as Predictive Biomarkers for Early-onset Neonatal Sepsis [J].
Zhang, Shujian ;
Luan, Xue ;
Zhang, Wei ;
Jin, Zhengyong .
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN, 2021, 31 (07) :821-824
[19]   Prognostic Value of PLR in Various Cancers: A Meta-Analysis [J].
Zhou, Xin ;
Du, Yiping ;
Huang, Zebo ;
Xu, Jun ;
Qiu, Tianzhu ;
Wang, Jian ;
Wang, Tongshan ;
Zhu, Wei ;
Liu, Ping .
PLOS ONE, 2014, 9 (06)
[20]   Inflammasome components and ADAMTS4 in premature rupture of membranes [J].
Zhu, Jinming ;
Ma, Chunling ;
Luan, Xiaomei ;
Li, Juan ;
Peng, Fengyun ;
Huang, Lei .
MOLECULAR MEDICINE REPORTS, 2021, 23 (02)