High-grade serous epithelial ovarian cancer, BRCA negative, in two 18-year-old women: case report

被引：0
|
作者：
Cortes-Esteban, Patricia [1 ]
Gomez-Avalos, Julieta [2 ]
Millan-Aguilar, Hugo [3 ]
Adame-Gonzalez, Ignacio [4 ]
Jasso-Sosa, Velma [5 ]
机构：
[1] ISSSTE, Dept Oncol Med, Ctr Med Nacl Noviembre 20, Clin Tumores Ginecol, Mexico City, Mexico
[2] ISSSTE, Dept Oncol Med, Ctr Med Nacl Noviembre 20, Mexico City, Mexico
[3] Fdn Canc Mama, Dept Oncol Med, Mexico City, Mexico
[4] ISSSTE, Dept Med Nucl, Ctr Med Nacl Noviembre 20, Mexico City, Mexico
[5] ISSSTE, Dept Anat Patol, Ctr Med Nacl Noviembre 20, Mexico City, Mexico
来源：
GACETA MEXICANA DE ONCOLOGIA | 2023年 / 22卷
关键词：
Ovarian cancer; BRCA; PARP inhibitor; BEVACIZUMAB;
D O I：
10.24875/j.gamo.220000951
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Two previously healthy 18-year-old Mexican women referred for medical evaluation due to ascites. Clinical studies revealed the presence of ovarian-dependent tumors, and elevated CA-125. A diagnostic laparotomy was performed, with a pathology report of a high-grade papillary serous adenocarcinoma. BRCA 1 and 2 was performed and reported negative for both patients. Chemotherapy and antiangiogenic treatment were started. One of the patients was considered a candidate for a poly (ADP-ribose) polymerase inhibitor.
引用
收藏
页码：41 / 46
页数：6
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