Management of Psoriatic Arthritis in Patients With Comorbidities: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations

被引：14

作者：

Campanholo, Cristiano B.

Maharaj, Ajesh B. ^{[1
]}

Corp, Nadia ^{[2
]}

Bell, Stacie ^{[3
]}

Costa, Luisa ^{[4
]}

de Vlam, Kurt ^{[5
]}

Gullick, Nicola J. ^{[6
,7
]}

Khraishi, Majed ^{[8
]}

Kishimoto, Mitsumasa ^{[9
]}

Palmou-Fontana, Natalia ^{[10
]}

Reddy, Soumya ^{[11
]}

Scarpa, Raffaele ^{[12
]}

Vega, Luis ^{[13
]}

Duarte, Gleison Vieira ^{[14
]}

Zisman, Devy ^{[15
,16
]}

Windt, Danielle A. van der ^{[17
]}

Duruoz, Mehmet T. ^{[18
]}

Ogdie, Alexis ^{[19
]}

机构：

[1] Life Westville Hosp, Life Healthcare, Westville, South Africa

[2] Keele Univ, Sch Med, Primary Care Ctr Versus Arthrit, Keele, Staffs, England

[3] Natl Psoriasis Fdn, Portland, OR USA

[4] Univ Naples Federico II, Dept Clin Med & Surg, Naples, Italy

[5] Univ Hosp Leuven, Dept Rheumatol, Leuven, Belgium

[6] Univ Warwick, Univ Hosp Coventry Warwickshire, Dept Rheumatol, Coventry, W Midlands, England

[7] Univ Warwick, Warwick Med Sch, Coventry, W Midlands, England

[8] Mem Univ Newfoundland, St John, NF, Canada

[9] Kyorin Univ, Dept Nephrol & Rheumatol, Sch Med, Tokyo, Japan

[10] Marques Valdecilla Univ Hosp, Rheumatol Deparment, Cantabria, Spain

[11] NYU, Grossman Sch Med, New York, NY USA

[12] Univ Naples Federico II, Dept Clin Med & Surg, Naples, Italy

[13] Cent Hosp Peruvian Air Force, Rheumatol Sect, Lima, Peru

[14] Inst Bahiano Imunoterapia, Dermatol Div IBIS, Salvador, BA, Brazil

[15] Carmel Hosp, Rheumatol Unit, Techn, Haifa, Israel

[16] Ruth & Bruce Rappaport Fac Med, Techn, Haifa, Israel

[17] Keele Univ, Sch Med, Primary Care Ctr Versus Arthrit, Keele, Staffs, England

[18] Marmara Univ, Div Rheumatol, PMR Dept, Sch Med, Istanbul, Turkiye

[19] Univ Penn, Perelman Sch Med, Philadelphia, PA USA

来源：

JOURNAL OF RHEUMATOLOGY | 2023年 / 50卷 / 03期

关键词：

comorbidities; GRAPPA; psoriatic arthritis; treatments; METABOLIC SYNDROME; RHEUMATOID-ARTHRITIS; INCREASED PREVALENCE; WEIGHT-LOSS; TNF-ALPHA; RISK; DISEASE; SECUKINUMAB; METHOTREXATE; MALIGNANCY;

D O I：

10.3899/jrheum.220310

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective. The 2021 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations provide an evidence-based guide for selecting therapy based on the individual's disease features. Beyond the disease features and associated conditions (eg, uveitis and inflammatory bowel disease), comorbidities play an important role in selecting therapy for an individual patient.Methods. We performed a systematic literature review. We examined the available evidence to inform treat-ment selection based on the presence or absence of comorbidities in psoriatic arthritis (PsA). Results. Common comorbidities in PsA that may affect treatment selection include presence of baseline car-diovascular disease (CVD) or high risk for CVD, obesity and metabolic syndrome, liver disease, mood dis-orders, including depression in particular, chronic infections, malignancies, osteoporosis, and fibromyalgia and/or central sensitization.Conclusion. Comorbidities may influence both the effectiveness of a given therapy but also the potential for adverse events. It is important to assess for the presence of comorbidities prior to therapy selection.

引用

页码：426 / 432

页数：7

共 50 条

[1] Hepatotoxicity rates do not differ in patients with rheumatoid arthritis and psoriasis treated with methotrexate [J].