Single cell transcriptomics reveals putative tumor promoting subpopulation in Brca1 mutant breast cancer mouse model

被引:0
|
作者
Pathania, Shailja
Rivera, Joshua
Tran, Stevension
Li, Carman Man Chung
Brugge, Joan
Zarringhalam, Kourosh
机构
关键词
D O I
10.1158/1538-7445.ADVBC23-A065
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A065
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Single cell RNA transcriptomics reveals tumor promoting mammary cell subpopulation upon replication stress in BRCA1 mutant breast cancer mouse model
    Pathania, Shailja
    Rivera, Joshua
    Khalid, Delan
    Manne, Monica
    Tran, Stevenson
    Kibaja, Kemmie
    Li, Carman M. C.
    Brugge, Joan
    CANCER RESEARCH, 2022, 82 (04)
  • [2] BRCA1 – Conductor of the Breast Stem Cell Orchestra: The Role of BRCA1 in Mammary Gland Development and Identification of Cell of Origin of BRCA1 Mutant Breast Cancer
    Niamh E. Buckley
    Paul B. Mullan
    Stem Cell Reviews and Reports, 2012, 8 : 982 - 993
  • [3] BRCA1-Conductor of the Breast Stem Cell Orchestra: The Role of BRCA1 in Mammary Gland Development and Identification of Cell of Origin of BRCA1 Mutant Breast Cancer
    Buckley, Niamh E.
    Mullan, Paul B.
    STEM CELL REVIEWS AND REPORTS, 2012, 8 (03) : 982 - 993
  • [4] Tracking the path of breast tumorigenesis in BRCA1 mutant breast cancer
    Rivera, Joshua
    Khalid, Delan
    Tran, Stevenson
    Kibaja, Kemmie
    Pathania, Shailja
    CANCER RESEARCH, 2020, 80 (11) : 71 - 72
  • [5] Single-Cell RNA Sequencing Reveals the Cellular Origin and Evolution of Breast Cancer in BRCA1 Mutation
    Hu, Li
    Su, Liming
    Cheng, Hainan
    Mo, Chunling
    Ouyang, Tao
    Li, Jinfeng
    Wang, Tianfeng
    Fan, Zhaoqing
    Fan, Tie
    Lin, Benyao
    Zhang, Jianguang
    Xie, Yuntao
    CANCER RESEARCH, 2021, 81 (10) : 2600 - 2611
  • [6] Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer
    Li, Carman Man-Chung
    Cordes, Alyssa
    Oliphant, Michael U. J.
    Quinn, S. Aidan
    Thomas, Mayura
    Selfors, Laura M.
    Silvestri, Francesca
    Girnius, Nomeda
    Rinaldi, Gianmarco
    Zoeller, Jason J.
    Shapiro, Hana
    Tsiobikas, Christina
    Gupta, Kushali P.
    Pathania, Shailja
    Regev, Aviv
    Kadoch, S. Cigall
    Muthuswamy, Senthil K.
    Brugge, Joan S.
    NATURE GENETICS, 2024, 56 (12) : 2842 - 2842
  • [7] Mouse models of BRCA1 and their application to breast cancer research
    Jennifer Dine
    Chu-Xia Deng
    Cancer and Metastasis Reviews, 2013, 32 : 25 - 37
  • [8] Mouse models of BRCA1 and their application to breast cancer research
    Dine, Jennifer
    Deng, Chu-Xia
    CANCER AND METASTASIS REVIEWS, 2013, 32 (1-2) : 25 - 37
  • [9] LURBINECTEDIN IS ACTIVE IN PATIENTS WITH BRCA1/2 MUTANT BREAST CANCER
    不详
    CANCER DISCOVERY, 2018, 8 (11) : 1345 - 1345
  • [10] Histological Findings of Mammary Gland Development and Risk of Breast Cancer in BRCA1 Mutant Mouse Models
    Kim, Hyelim
    Moon, Woo Kyung
    JOURNAL OF BREAST CANCER, 2021, 24 (05) : 455 - 462