Antidiabetic medicinal plants from the Chenopodiaceae family: a comprehensive overview

被引:9
作者
Cherrada, Nezar [1 ,2 ]
Chemsa, Ahmed Elkhalifa [2 ,3 ]
Gheraissa, Noura [3 ,4 ]
Zaater, Abdelmalek [2 ,5 ]
Benamor, Bilal [4 ,6 ]
Ghania, Ahmed [1 ,7 ]
Yassine, Bouras [1 ,7 ]
Kaddour, Abdelbasset [3 ]
Afzaal, Muhammad [8 ]
Asghar, Aasma [9 ]
Saeed, Farhan [8 ]
Teferi Asres, Degnet [10 ]
机构
[1] Oued Univ, Fac Life & Nat Sci, Dept Mol & Cellular Biol, El Oued, Algeria
[2] El Oued Univ, Lab Biodivers & Applicat Biotechnol Agr, El Oued, Algeria
[3] El Oued Univ, Fac Life & Nat Sci, Dept Biol, El Oued, Algeria
[4] Higher Sch Saharian Agr El Oued, El Oued, Algeria
[5] Oued Univ, Fac Life & Nat Sci, Dept Agron, El Oued, Algeria
[6] Univ Mohamed Khider, Lab Genet Biotechnol & Valorizat Bioresources LGBV, Biskra, Algeria
[7] El Oued Univ, Lab Biol Environm & Hlth, El Oued, Algeria
[8] Govt Coll Univ Faisalabad, Dept Food Sci, 92QG MGF, Faisalabad, Punjab, Pakistan
[9] Govt Coll Univ Faisalabad, Dept Nutr Sci, Faisalabad, Pakistan
[10] Bahir Dar Univ, Bahir Dar Inst Technol, Bahir Dar Food & Nutr Res Ctr, Bahir Dar, Ethiopia
关键词
Antidiabetic plants; Chenopodiaceae; Medicinal plants; Bioactive compounds; Diabetes mellitus; Antihyperglycemic; ATRIPLEX-HALIMUS L; ANTIMICROBIAL ACTIVITIES; FLAVONOID GLYCOSIDES; TRAGANUM-NUDATUM; SUAEDA-MARITIMA; ESSENTIAL OIL; IN-VITRO; ANTIOXIDANT; EXTRACTS; ANTICHOLINESTERASE;
D O I
10.1080/10942912.2023.2301576
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Diabetes is a chronic disease that has affected millions of people worldwide. The current treatments for diabetes, such as insulin therapy and oral medications, have limitations, including adverse effects and high costs. Therefore, there is a need for new and effective treatments for diabetes. Recent studies have shown that plants from the Chenopodiaceae family have anti-diabetic properties. In this study, we have identified 22 plants from the Chenopodiaceae family that have been reported to have anti-diabetic properties. These plants contain various bioactive compounds, such as flavonoids, alkaloids, and phenols that have been shown to have anti-diabetic effects. Some of these compounds can enhance insulin secretion, improve glucose uptake, and reduce blood glucose levels. The anti-diabetic properties of these plants have been investigated in vitro and in vivo studies, and the results are promising. Several of these plants have been shown to reduce blood glucose levels in animal models of diabetes significantly. Overall, the findings of this study suggest that plants from the Chenopodiaceae family have potential as safe and effective treatment options for diabetes. Further research is needed to fully understand these plants' mechanisms of action and safety profile. However, these findings provide a promising avenue for developing new anti-diabetic drugs from natural sources. Specifically, I've outlined three significant mechanisms: stimulation of insulin secretion, enhancement of glucose uptake, and inhibition of gluconeogenesis, all of which are attributed to the bioactive compounds found in Chenopodiaceae medicinal plants.
引用
收藏
页码:194 / 213
页数:20
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