Aficamten for Drug-Refractory Severe Obstructive Hypertrophic Cardiomyopathy in Patients Receiving Disopyramide: REDWOOD-HCM Cohort 3

被引：14

作者：

Owens, Anjali T. ^{[1
,17
]}

Masri, Ahmad ^{[2
]}

Abraham, Theodore P. ^{[3
]}

Choudhury, Lubna ^{[4
]}

Rader, Florian ^{[5
]}

Symanski, John d. ^{[6
]}

Turer, Aslan T. ^{[7
]}

Wong, Timothy C. ^{[8
]}

Tower-rader, Albree ^{[9
]}

Coats, Caroline J. ^{[10
]}

Fifer, Michael A. ^{[11
]}

Olivotto, Iacopo ^{[12
]}

Solomon, Scott D. ^{[13
]}

Watkins, Hugh C. ^{[14
]}

Heitner, Stephen B. ^{[15
]}

Jacoby, Daniel L. ^{[15
]}

Kupfer, Stuart ^{[15
]}

Malik, Fady I. ^{[15
]}

Meng, Lisa ^{[15
]}

Sohn, Regina ^{[15
]}

Wohltman, Amy ^{[15
]}

Maron, Martin S. ^{[16
]}

机构：

[1] Univ Penn, Ctr Inherited Cardiovasc Dis, Perelman Sch Med, Div Cardiovasc Med,Dept Med, Philadelphia, PA USA

[2] Oregon Hlth & Sci Univ, Portland, OR USA

[3] Univ Calif San Francisco, San Francisco, CA USA

[4] Northwestern Univ, Feinberg Sch Med, Div Cardiol, Chicago, IL 60208 USA

[5] Cedars Sinai Med Ctr, Smidt Heart Inst, Los Angeles, CA USA

[6] Sanger Heart & Vasc Inst, Atrium Hlth, Charlotte, NC USA

[7] Univ Texas Southwestern Med Ctr, Dallas, TX USA

[8] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA

[9] Massachusetts Gen Hosp, Boston, MA USA

[10] Univ Glasgow, Sch Cardiovasc & Metab Hlth, Glasgow, Scotland

[11] Massachusetts Gen Hosp, Cardiol Div, Boston, MA USA

[12] Ist Ricovero & Cura Carattere Sci, Meyer Childrens Hosp, Florence, Italy

[13] Brigham & Womens Hosp, Boston, MA USA

[14] Univ Oxford, Oxford, England

[15] Cytokinetics, South San Francisco, CA USA

[16] Lahey Hosp & Med Ctr, Burlington, MA USA

[17] Univ Penn, Perelman Sch Med, Ctr Inherited Cardiovasc Dis, 3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA

来源：

JOURNAL OF CARDIAC FAILURE | 2023年 / 29卷 / 11期

关键词：

Aficamten; obstructive hypertrophic cardio-myopathy; refractory obstructive hypertrophic cardiomy-opathy; REDWOOD-HCM;

D O I：

10.1016/j.cardfail.2023.07.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1576 / 1582

页数：7

共 36 条

[1] EFFICACY AND SAFETY OF AFICAMTEN AND DISOPYRAMIDE COADMINISTRATION IN OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY: RESULTS FROM REDWOOD-HCM COHORT 3
Owens, Anjali Tiku
Masri, Ahmad
Abraham, Theodore P.
Choudhury, Lubna
Rader, Florian
Symanski, John D.
Turer, Aslan Teyfik
Wong, Timothy C.
Tower-Rader, Albree
Coats, Caroline
Fifer, Michael A.
Olivotto, Iacopo
Solomon, Scott D.
Watkins, Hugh
Robertson, Laura
Meng, Lisa
Paige, Sharon
Wohltman, Amy
Kupfer, Stuart
Malik, Fady I.
Heitner, Stephen B.
Maron, Martin S.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2022, 79 (09) : 244 - 244
[2] AFICAMTEN IN PATIENTS WITH SYMPTOMATIC NON-OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY (REDWOOD-HCM COHORT 4)
Masri, Ahmad
Sherrid, Mark V.
Choudhury, Lubna
Rader, Florian
Kramer, Christopher M.
Saberi, Sara
Wong, Timothy C.
Turer, Aslan Teyfi K.
Nagueh, Sherif F.
Owens, Anjali Tiku
Coats, Caroline
Olivotto, Iacopo
Watkins, Hugh
Fifer, Michael A.
Solomon, Scott D.
Abraham, Theodore P.
Heitner, Steve
Jacoby, Dan
Kupfer, Stuart
Malik, Fady I.
Meng, Lisa
Sohn, Regina L.
Wohltman, Amy
Maron, Martin S.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2023, 81 (08) : 609 - 609
[3] Efficacy and Safety of Aficamten in Symptomatic Nonobstructive Hypertrophic Cardiomyopathy: Results From the REDWOOD-HCM Trial, Cohort 4
Masri, Ahmad
Sherrid, Mark, V
Abraham, Theodore p.
Choudhury, Lubna
Garcia-pavia, Pablo
Kramer, Christopher M.
Barriales-villa, Roberto
Owens, Anjali T.
Rader, Florian
Nagueh, Sherif F.
Olivotto, Iacopo
Saberi, Sara
Tower-rader, Albree
Wong, Timothy c.
Coats, Caroline j.
Watkins, Hugh
Fifer, Michael a.
Solomon, Scott d.
Heitner, Stephen b.
Jacoby, Daniel l.
Kupfer, Stuart
Malik, Fady, I
Meng, Lisa
Sohn, Regina l.
Wohltman, Amy
Maron, Martins S.
JOURNAL OF CARDIAC FAILURE, 2024, 30 (11) : 1439 - 1448
[4] Therapeutic options in patients with obstructive hypertrophic cardiomyopathy and severe drug-refractory symptoms
Ten Berg, JM
Van Tooren, R
Jaarsma, W
Suttorp, MJ
Plokker, HWM
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1998, 32 (05) : 1485 - 1485
[5] Therapeutic options in patients with obstructive hypertrophic cardiomyopathy and severe drug-refractory symptoms
Fananapazir, L
McAreavey, D
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1998, 31 (02) : 259 - 264
[6] Standard-of-Care Medication Withdrawal in Patients With Obstructive Hypertrophic Cardiomyopathy Receiving Aficamten in FOREST-HCM
Masri, Ahmad
Choudhury, Lubna
Barriales-Villa, Roberto
Elliott, Perry
Maron, Martin S.
Nassif, Michael E.
Oreziak, Artur
Owens, Anjali Tiku
Saberi, Sara
Tower-Rader, Albree
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Garcia-Pavia, Pablo
Olivotto, Iacopo
Nagueh, Sherif F.
Wang, Andrew
Heitner, Stephen B.
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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2024, 84 (19) : 1839 - 1849
[7] Baseline Characteristics of Patients in SEQUOIA-HCM: APhase 3 Trial of Aficamten in Obstructive Hypertrophic Cardiomyopathy
Maron, Martin S.
Abraham, Theodorep.
Coats, Caroline J.
Olivotto, Iacopo
Lee, Matthewm. Y.
Arad, Michael
Cardim, Nuno
Ma, Chang-Sheng
Choudhury, Lubna
Duengen, Hans-Dirk
Garcia-Pavia, Pablo
Hagege, Albert
Lewis, Gregory D.
Michels, Michelle
Oreziak, Artur
Owens, Anjali T.
Tfelt-Hansen, Jacob
Veselka, Josef
Watkins, Hugh C.
Heitner, Stephen B.
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Meng, Lisa
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JOURNAL OF CARDIAC FAILURE, 2024, 30 : S3 - S3
[8] Contemporary Septal Reduction Therapy in Drug-Refractory Hypertrophic Obstructive Cardiomyopathy
Maekawa, Yuichiro
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Takanashi, Shuichiro
CIRCULATION JOURNAL, 2018, 82 (08) : 1977 - 1984
[9] Percutaneous Intramyocardial Septal Radiofrequency Ablation in Patients With Drug-Refractory Hypertrophic Obstructive Cardiomyopathy
Zhou, Mengyao
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Hsi, David H.
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[10] Cardiac Myosin Inhibitors as an effective pharmacological treatment for patients of severe drug-refractory hypertrophic cardiomyopathy
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