Immunotherapy for deficient mismatch repair (dMMR) pancreatic ductal adenocarcinoma

被引：2
作者：
Ebia, Matthew I. [1 ]
Hitchins, Megan P. [2 ]
Hendifar, Andrew E. [1 ,3 ,4 ]
机构：
[1] Cedars Sinai Med Ctr, Dept Med, Div Hematol & Oncol, Los Angeles, CA USA
[2] Cedars Sinai Med Ctr, Dept Biomed Sci, Los Angeles, CA USA
[3] Cedars Sinai Samuel Oschin Comprehens Canc Inst, Los Angeles, CA USA
[4] Cedars Sinai Med Ctr, Dept Med, Div Hematol & Oncol, 8700 Beverly Blvd,Suite 1042AC, Los Angeles, CA 90048 USA
来源：
JOURNAL OF GASTROINTESTINAL ONCOLOGY | 2023年 / 14卷 / 02期
关键词：
Pancreatic ductal adenocarcinoma (PDAC); DNA deficient mismatch repair (DNA dMMR); microsatellite instability (MSI); Lynch syndrome; immunotherapy; CANCER;
D O I：
10.21037/jgo-23-12
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：1175 / 1177
页数：3
相关论文
共 50 条
  • [1] A Patient With Locally Advanced Mismatch-Repair-Deficient Pancreatic Ductal Adenocarcinoma Successfully Treated With Neoadjuvant Immunotherapy
    Cox, Ronald E., Jr.
    Mahipal, Amit
    Chakrabarti, Sakti
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2021, 13 (04)
  • [2] Frequency of mismatch repair deficiency in pancreatic ductal adenocarcinoma
    Ahmad-Nielsen, Soz Abdulrahman
    Nielsen, Michael Friberg Bruun
    Mortensen, Michael Bau
    Detlefsen, Sonke
    PATHOLOGY RESEARCH AND PRACTICE, 2020, 216 (06)
  • [3] Immunotherapy for pancreatic ductal adenocarcinoma
    Carpenter, Eileen
    Nelson, Sarah
    Bednar, Filip
    Cho, Clifford
    Nathan, Hari
    Sahai, Vaibhav
    di Magliano, Marina Pasca
    Frankel, Timothy L.
    JOURNAL OF SURGICAL ONCOLOGY, 2021, 123 (03) : 751 - 759
  • [4] Epigenetic modulation enhances immunotherapy for pancreatic ductal adenocarcinoma
    Li, Yan
    Hong, Young K.
    Wang, Xingtong
    Pandit, Harshul
    Zheng, Qianqian
    Yu, Youxi
    Shi, Xiaoju
    Chen, Yujia
    Tan, Min
    Pulliam, Zachary
    Bhutiani, Neal
    Lin, Andrew
    Badach, Jeremy
    Zhang, Ping
    Martin, Robert C. G.
    CLINICAL & TRANSLATIONAL IMMUNOLOGY, 2022, 11 (12)
  • [5] Advances in immunotherapy for pancreatic ductal adenocarcinoma
    Miyazawa, Motoki
    Katsuda, Masahiro
    Kawai, Manabu
    Hirono, Seiko
    Okada, Ken-ichi
    Kitahata, Yuji
    Yamaue, Hiroki
    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 2021, 28 (05) : 419 - 430
  • [6] PD-L1 expression and deficient mismatch repair in ductal adenocarcinoma of the prostate
    Lindh, Claes
    Kis, Lorand
    Delahunt, Brett
    Samaratunga, Hemamali
    Yaxley, John
    Wiklund, Nils Peter
    Clements, Mark
    Egevad, Lars
    APMIS, 2019, 127 (08) : 554 - 560
  • [7] Use of Chemoimmunotherapy for Locally Advanced Deficient Mismatch Repair (dMMR) Gastric Adenocarcinoma With Curative Intent: A Case Report
    Diez, Beatriz Gonzalez
    Acenero, Maria Jesus Fernandez
    Mendez, Ramiro Jesus
    Martin-Antona, Esteban
    Sastre, Javier
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2024, 16 (06)
  • [8] Developments in Checkpoint Inhibitor Therapy for the Management of Deficient Mismatch Repair (dMMR) Rectal Cancer
    Su, Alan
    Pedraza, Rodrigo
    Kennecke, Hagen
    CURRENT ONCOLOGY, 2023, 30 (04) : 3672 - 3683
  • [9] A rare case of sporadic mismatch repair deficient pancreatic ductal adenocarcinoma that responded to ipilimumab and nivolumab combination treatment: case report
    Han, Margaret Y.
    Borazanci, Erkut
    JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2023, 14 (01) : 458 - 462
  • [10] Clinical and Genetic Implications of DNA Mismatch Repair Deficiency in Patients With Pancreatic Ductal Adenocarcinoma
    Cloyd, Jordan M.
    Katz, Matthew H. G.
    Wang, Huamin
    Cuddy, Amanda
    You, Y. Nancy
    JAMA SURGERY, 2017, 152 (11) : 1086 - 1088
12345