Catalyst-free visible-light-induced decarbonylative C-H alkylation of quinoxalin-2(1H)-ones

被引：28
|
作者：
Shi, Xiaodi [1 ]
Cao, Yunpeng [1 ]
Liu, Yuxiu [1 ]
Niu, Kaikai [1 ]
Song, Hongjian [1 ]
Zhang, Jingjing [1 ,2 ]
Wang, Qingmin [1 ]
机构：
[1] Nankai Univ, Res Inst Elemento Organ Chem, Frontiers Sci Ctr New Organ Matter, Coll Chem,State Key Lab Elemento Organ Chem, Tianjin 300071, Peoples R China
[2] Tianjin Agr Univ, Coll Basic Sci, Tianjin 300392, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2023年 / 10卷 / 05期
基金：
中国国家自然科学基金;
关键词：
METAL; FUNCTIONALIZATION; INHIBITORS; DESIGN; AMINES; THIOLS; ACIDS;
D O I：
10.1039/d2qo02019j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Direct functionalization of C(sp(3))-H bonds is an effective, straightforward method for accessing a diverse array of heteroarene derivatives. However, its wide application is limited by the need for the use of catalysts or oxidants. In this study, we developed a mild, eco-friendly, practical photochemical protocol for decarbonylative C-H alkylation reactions of quinoxalin-2(1H)-ones and aliphatic aldehydes with air as the oxidant at room temperature. These catalyst- and oxidant-free reactions showed good functional-group tolerance and a broad substrate scope.
引用
收藏
页码：1296 / 1300
页数：5
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