The effect of vitamin D deficiency on glycemic control in patients with type 2 diabetes mellitus

被引：1

作者：

Mostafa, Neveen Rashad ^{[1
]}

Ali, Abeer Ahmed Mohamed ^{[2
]}

Marzo, Roy Rillera ^{[3
,4
]}

机构：

[1] Alexandria Univ, Dept Internal Med, Med Res Inst, Alexandria, Egypt

[2] Alexandria Univ, Med Res Inst, Dept Chem Pathol, Alexandria, Egypt

[3] Management & Sci Univ, Int Med Sch, Dept Community Med, Shah Alam, Malaysia

[4] Monash Univ Malaysia, Jeffrey Cheah Sch Med & Hlth Sci, Global Publ Hlth, Kuala Lumpur, Malaysia

来源：

HEALTHCARE IN LOW-RESOURCE SETTINGS | 2023年 / 11卷

关键词：

vitamin D; diabetes mellitus type 2; glycemic control; inflammation;

D O I：

10.4081/hls.2023.11340

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Multiple factors are involved in the development of type 2 dia-betes mellitus (T2DM), but an imbalance between free radical for-mation and antioxidant removal is the main cause of diabetic com-plications. Micronutrients with antioxidant properties may have a role in the development of diabetes mellitus (DM) and its compli-cations. Vitamin D has recently been found to have membrane antioxidant effect and a relationship to the development of T2DM, as it can modify its risk. Whether vitamin D deficiency has an effect on hyperglycemia in diabetic patients or not need further study. Our aim was to examine the effect of vitamin D deficiency on glycemic control in T2DM. We examined the vitamin D levels of 100 patients with T2DM and correlated them with fasting blood sugar and glycated hemoglobin A1c (HbA1c) levels. High levels of fasting blood sugar and HbA1c levels were significantly asso-ciated with vitamin D deficiency. Vitamin D deficiency negatively affects glycemic control in patients with T2DM.

引用

页数：4

共 28 条

[21] Calcitriol/calcifediol ratio: An indicator of vitamin D hydroxylation efficiency? [J].

Pasquali, Marzia ;

Tartaglione, Lida ;

Rotondi, Silverio ;

Muci, Maria Luisa ;

Mandanici, Giusi ;

Farcomeni, Alessio ;

Marangella, Martino ;

Mazzaferro, Sandro .

BBA CLINICAL, 2015, 3 :251-256

[22]

Peterkova V. A., 2015, Problemy Endokrinologii, V61, P39, DOI 10.14341/probl201561239-44

[23] Clinical diagnostic tools for vitamin D assessment [J].

Shah, Iltaf ;

Akhtar, M. Kalim ;

Hisaindee, Soleiman ;

Rauf, Muhammad A. ;

Sadig, Mohammed ;

Ashraf, S. Salman .

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2018, 180 :105-117

[24] Analysis of Association between Vitamin D Deficiency and Insulin Resistance [J].

Szymczak-Pajor, Izabela ;

Sliwinska, Agnieszka .

NUTRIENTS, 2019, 11 (04)

[25] Vitamins and Type 2 Diabetes Mellitus [J].

Valdes-Ramos, Roxana ;

Ana Laura, Guadarrama-Lopez ;

Beatriz Elina, Martinez-Carrillo ;

Alejandra Donaji, Benitez-Arciniega .

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS, 2015, 15 (01) :54-63

[26] Relationship between 25-Hydroxyvitamin D and Newly Diagnosed Type 2 Diabetes Mellitus in Postmenopausal Women with Osteoporosis [J].

Vujosevic, Snezana ;

Borozan, Sanja ;

Radojevic, Nemanja ;

Aligrudic, Svetlana ;

Bozovic, Dragica .

MEDICAL PRINCIPLES AND PRACTICE, 2014, 23 (03) :229-233

[27]

Zatalia St Rabiul, 2013, Acta Med Indones, V45, P141

[28] The Relationship Between Vitamin D Deficiency and Glycated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus [J].

Zhao, Hang ;

Zhen, Yunfeng ;

Wang, Zijing ;

Qi, Licui ;

Li, Yong ;

Ren, Luping ;

Chen, Shuchun .

DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2020, 13 :3899-3907

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