The interplay between macronutrients and sleep: focus on circadian and homeostatic processes

被引：4

作者：

Gangitano, Elena ^{[1
,2
]}

Baxter, Matthew ^{[1
,3
]}

Voronkov, Maria ^{[1
]}

Lenzi, Andrea ^{[2
]}

Gnessi, Lucio ^{[2
]}

Ray, David ^{[1
,3
]}

机构：

[1] Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Oxford, Oxfordshire, England

[2] Sapienza Univ Rome, Dept Expt Med, Rome, Italy

[3] John Radcliffe Hosp, Natl Inst Hlth Res Oxford Biomed Res Ctr, Oxford, Oxfordshire, England

来源：

FRONTIERS IN NUTRITION | 2023年 / 10卷

关键词：

sleep; macronutrients; circadian process; homeostatic process; process C; process S; clock; protein; HIGH-FAT DIET; ACTIVATED PROTEIN-KINASE; BODY-MASS INDEX; SLOW-WAVE SLEEP; ENERGY-METABOLISM; SUPRACHIASMATIC NUCLEUS; WAIST CIRCUMFERENCE; INSUFFICIENT SLEEP; AROUSAL THRESHOLDS; GENE-EXPRESSION;

D O I：

10.3389/fnut.2023.1166699

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Sleep disturbances are an emerging risk factor for metabolic diseases, for which the burden is particularly worrying worldwide. The importance of sleep for metabolic health is being increasingly recognized, and not only the amount of sleep plays an important role, but also its quality. In this review, we studied the evidence in the literature on macronutrients and their influence on sleep, focusing on the mechanisms that may lay behind this interaction. In particular, we focused on the effects of macronutrients on circadian and homeostatic processes of sleep in preclinical models, and reviewed the evidence of clinical studies in humans. Given the importance of sleep for health, and the role of circadian biology in healthy sleep, it is important to understand how macronutrients regulate circadian clocks and sleep homeostasis.

引用

页数：14

共 186 条

[1] Lithium lengthens the circadian period of individual suprachiasmatic nucleus neurons [J].