FDG-Avid But Pentixafor-Negative in EBV-Associated T-Cell Lymphoproliferative Disorders

被引：3
作者：
Shu, Qiaoqiao [1 ,2 ,3 ]
He, Xubing [1 ,2 ,3 ]
Chen, Yue [1 ,2 ,3 ]
Cai, Liang [1 ,2 ,3 ]
机构：
[1] Southwest Med Univ, Dept Nucl Med, Affiliated Hosp, 25 TaiPing St, Luzhou 646000, Sichuan, Peoples R China
[2] Nucl Med & Mol Imaging Key Lab Sichuan Prov, Luzhou, Sichuan, Peoples R China
[3] Southwest Med Univ, Inst Nucl Med, Luzhou, Sichuan, Peoples R China
来源：
CLINICAL NUCLEAR MEDICINE | 2023年 / 48卷 / 08期
关键词：
hemophagocytic lymphohistiocytosis; lymphoproliferative disorders; F-18-FDG; Ga-68-pentixafor; PET/CT; HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS;
D O I：
10.1097/RLU.0000000000004747
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
An 18-year-old woman with intermittent fever, pancytopenia, abnormal liver function, and enlarged lymph nodes and hepatosplenomegaly was clinically suspected as hemophagocytic lymphohistiocytosis. F-18-FDG PET/CT showed increased metabolism in multiple lymph nodes, which were highly suggestive of lymphoma. No increased CXCR4 expression in lymph nodes was demonstrated on Ga-68-pentixafor PET/CT. Subsequent right neck lymph node biopsy pathology revealed EBV-associated lymphoproliferative disorders. Our case shows that Ga-68-pentixafor PET/CT may have potential value in differentiating EBV-associated lymphoproliferative disorders from lymphomas.
引用
收藏
页码：714 / 715
页数：2
相关论文
共 45 条
  • [31] Spectrum of Epstein-Barr virus-associated T-cell lymphoproliferative disorder in adolescents and young adults in Taiwan
    Wang, Ren-Ching
    Chang, Sheng-Tsung
    Hsieh, Yen-Chuan
    Huang, Wan-Ting
    Hsu, Jeng-Dong
    Tseng, Chih-En
    Wang, Ming-Chung
    Hwang, Wei-Shou
    Wang, John
    Chuang, Shih-Sung
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2014, 7 (05): : 2430 - 2437
  • [32] Hematopoietic Stem Cell Transplantation for the Treatment of Epstein-Barr Virus-Associated T- or NK-Cell Lymphoproliferative Diseases and Associated Disorders
    Sawada, Akihisa
    Inoue, Masami
    FRONTIERS IN PEDIATRICS, 2018, 6
  • [33] The first case of methotrexate-associated lymphoproliferative disorder presenting as follicular T-cell lymphoma
    Muto, Reiji
    Kawakita, Toshiro
    Miyoshi, Hiroaki
    Arakawa, Fumiko
    Nakashima, Kazutaka
    Ohshima, Koichi
    Murayama, Toshihiko
    PATHOLOGY INTERNATIONAL, 2021, 71 (11) : 765 - 770
  • [34] Severe Hemorrhagic Coagulopathy With Hemophagocytic Lymphohistiocytosis Secondary to Epstein-Barr Virus-Associated T-Cell Lymphoproliferative Disorder
    Nawathe, Pooja A.
    Ravindranath, Thyyar M.
    Satwani, Prakash
    Baird, J. Scott
    PEDIATRIC CRITICAL CARE MEDICINE, 2013, 14 (04) : E176 - E181
  • [35] XMEN-associated Systemic EBV-positive T-cell Lymphoma of Childhood: Report of Two Cases and Literature Review
    Cao, Ping
    Zhang, Xiao
    Fu, Yang
    Wang, Hongsheng
    Yu, Yi
    Zhu, Xiaohua
    Jiang, Junye
    Zhai, Xiaowen
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2024, 46 (07) : 356 - 363
  • [36] Clinicopathological states of Epstein-Barr virus-associated T/NK-cell lymphoproliferative disorders (severe chronic active EBV infection) of children and young adults
    Suzuki, K
    Ohshima, K
    Karube, K
    Suzumiya, J
    Ohga, S
    Ishihara, S
    Tamura, K
    Kikuchi, M
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2004, 24 (05) : 1165 - 1174
  • [37] Human T-cell lymphotropic virus type I infection in patients with lymphoproliferative disorders at two sentinel sites in Cuba
    Diaz Torrez, Hector M.
    Alvarez Vega, Nereyda
    Munio Perurena, Jorge E.
    Lubian Caballero, Ana Luisa
    Martin Alfonso, Dayami
    Diaz Herrera, Dervel F.
    Blanco de Armas, Madelin
    REVISTA PANAMERICANA DE SALUD PUBLICA-PAN AMERICAN JOURNAL OF PUBLIC HEALTH, 2010, 27 (01): : 17 - 22
  • [38] Peripheral T-cell Lymphomas of Follicular T-Helper Cell Derivation With Hodgkin/Reed-Sternberg Cells of B-cell Lineage Both EBV-positive and EBV-negative Variants Exist
    Nicolae, Alina
    Pittaluga, Stefania
    Venkataraman, Girish
    Vijnovich-Baron, Anahi
    Xi, Liqiang
    Raffeld, Mark
    Jaffe, Elaine S.
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2013, 37 (06) : 816 - 826
  • [39] CD30-Positive T-Cell Lymphoproliferative Disease of the Oral Mucosa in Children: A Manifestation of Epstein-Barr Virus-Associated T-Lymphoproliferative Disorder
    Hong, Mineui
    Ko, Young Hyeh
    JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE, 2015, 49 (06) : 525 - 530
  • [40] Methotrexate-associated lymphoproliferative disorders with angioimmunoblastic T-cell lymphoma-like features accompanied by gamma-heavy chain disease in a patient with rheumatoid arthritis
    Kiyasu, Junichi
    Arakawa, Fumiko
    Haji, Shojiro
    Tachikawa, Yoshimichi
    Tsuda, Mariko
    Tsukamoto, Yasuhiro
    Ikeda, Motohiko
    Muta, Hiroki
    Matsushima, Takamitsu
    Miyoshi, Hiroaki
    Shiratsuchi, Motoaki
    Ogawa, Yoshihiro
    Ohshima, Kouichi
    Yufu, Yuji
    PATHOLOGY INTERNATIONAL, 2018, 68 (08) : 485 - 490
12345