Unmet needs and future perspectives in hydroxychloroquine retinopathy

被引:0
|
作者
Yusuf, Imran H. [1 ,2 ]
Charbel Issa, Peter [1 ,2 ]
Ahn, Seong Joon [3 ]
机构
[1] Univ Oxford, Oxford Eye Hosp, John Radcliffe Hosp, Oxford, England
[2] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Neurosci, Oxford, England
[3] Hanyang Univ, Hanyang Univ Hosp, Dept Ophthalmol, Coll Med, Seoul, South Korea
基金
英国医学研究理事会; 新加坡国家研究基金会;
关键词
hydroxychloroquine; perspectives; retinal toxicity; screening; unmet needs; natural history; definition; COMBINED AUTOPHAGY; CHLOROQUINE; INHIBITION; TRIAL;
D O I
10.3389/fmed.2023.1196815
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Retinopathy is a well-recognized toxic effect of hydroxychloroquine treatment. As hydroxychloroquine retinopathy is potentially a vision-threatening condition, early detection is imperative to minimize vision loss due to drug toxicity. However, early detection of hydroxychloroquine retinopathy is still challenging even with modern retinal imaging techniques. No treatment has been established for this condition, except for drug cessation to minimize further damage. In this perspective article, we aimed to summarize the knowledge gaps and unmet needs in current clinical practice and research in hydroxychloroquine retinopathy. The information presented in this article may help guide the future directions of screening practices and research in hydroxychloroquine retinopathy.
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页数:6
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