Prospective multicenter study on infectious complications and clinical outcome of 230 unfit acute myeloid leukemia patients receiving first-line therapy with hypomethylating agents alone or in combination with Venetoclax

被引:9
作者
Candoni, Anna [1 ]
Lazzarotto, Davide [2 ]
Papayannidis, Cristina [3 ]
Piccini, Matteo [4 ]
Nadali, Giampaolo [5 ]
Dargenio, Michelina [6 ]
Riva, Marta [7 ]
Fracchiolla, Nicola [8 ]
Mellillo, Lorella [9 ]
Dragonetti, Giulia [10 ]
Del Principe, Maria Ilaria [11 ]
Cattaneo, Chiara [12 ]
Stulle, Manuela [13 ]
Pasciolla, Crescenza [14 ]
De Marchi, Roberta [15 ]
Delia, Mario [16 ]
Tisi, Maria Chiara [17 ]
Bonuomo, Valentina [5 ]
Sciume, Mariarita [7 ]
Spadea, Antonio [18 ]
Sartor, Chiara [3 ]
Griguolo, Davide [13 ]
Buzzatti, Elisa [11 ]
Basilico, Claudia Maria [19 ]
Sarlo, Chiara [20 ]
Piccioni, Anna Lina [21 ]
Cerqui, Elisa [12 ]
Lessi, Federica [22 ]
Olivieri, Attilio [23 ]
Fanin, Renato [2 ]
Luppi, Mario [1 ]
Pagano, Livio [10 ]
机构
[1] Univ Modena & Reggio Emilia, Azienda Osped Univ Modena, Dept Med & Surg Sci, Sect Hematol, Modena, Italy
[2] Univ Udine, Div Hematol & Stem Cell Transplantat, ASUFC, Udine, Italy
[3] Univ Bologna, Inst Hematol & Med Oncol L&A Seragnoli, Bologna, Italy
[4] Azienda Osped Univ Careggi, Div Hematol, Florence, Italy
[5] Policlin GB Rossi, Div Hematol, AOUI, Verona, Italy
[6] Osped Vito Fazzi, Div Hematol, Lecc, Italy
[7] ASST Grande Osped Metropolitano, Dipartimento Ematol Oncol, Niguarda Canc Ctr, Milan, Italy
[8] Univ Milan, Fdn IRCCS CaGranda Osped Maggiore Policlin, UO Oncoematol, Milan, Italy
[9] Foggia & IRCCS Casa Sollievo Sofferenza, Div Hematol, San Giovanni Rotondo, Italy
[10] Univ Cattolica Sacro Cuore, Fdn Policlin A Gemelli IRCCS, Div Hematol, Polo Onco Ematol, Rome, Italy
[11] Fdn Policlin Tor Vergata, Hematol, Rome, Italy
[12] Spedali Civil Brescia, Sect Hematol, Brescia, Italy
[13] ASUGI, Div Hematol, Trieste, Italy
[14] IRCCS Ist Tumori Giovanni Paolo II, Haematol Unit, Bari, Italy
[15] IRCCS, Veneto Inst Oncol IOV, Dept Oncol, Onco Hematol, Padua, Italy
[16] Univ Bari, Hematol & Bone Marrow Transplantat Unit, Azienda Osped Univ Consorziale Policlin, Bari, Italy
[17] Univ Milan, San Bortolo Hosp Vicenza, Fdn IRCCS CaGranda Osped Maggiore Policlin, Cell Therapy & Hematol,7UO Oncoematol, Milan, Italy
[18] IRCCS Regina Elena Natl Canc Inst, Hematol & Stem Cell Transplant Unit, Rome, Italy
[19] Osped Circolo & Fdn Macchi, Div Hematol, ASST Sette Laghi, Varese, Italy
[20] Univ Campus Biomed, Hematol & Stem Cell Transplantat Unit, Rome, Italy
[21] Azienda Osped San Giovanni Addolorata, Dipartimento Ematol, Rome, Italy
[22] Azienda Osped Univ Padova, Dept Med, Hematol Unit, DIMED, Padua, Italy
[23] Azienda Osped Univ Osped Riuniti Ancona, Div Hematol, Ancona, Italy
关键词
D O I
10.1002/ajh.26846
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E80 / E83
页数:4
相关论文
共 6 条
  • [1] Invasive fungal infections in acute myeloid leukemia treated with venetoclax and hypomethylating agents
    Aldoss, Ibrahim
    Dadwal, Sanjeet
    Zhang, Jianying
    Tegtmeier, Bernard
    Mei, Matthew
    Arslan, Shukaib
    Al Malki, Monzr M.
    Salhotra, Amandeep
    Ali, Haris
    Aribi, Ahmed
    Sandhu, Karamjeet
    Khaled, Samer
    Snyder, David
    Nakamura, Ryotaro
    Stein, Anthony S.
    Forman, Stephen J.
    Marcucci, Guido
    Pullarkat, Vinod
    [J]. BLOOD ADVANCES, 2019, 3 (23) : 4043 - 4049
  • [2] Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia
    DiNardo, C. D.
    Jonas, B. A.
    Pullarkat, V.
    Thirman, M. J.
    Garcia, J. S.
    Wei, A. H.
    Konopleva, M.
    Doehner, H.
    Letai, A.
    Fenaux, P.
    Koller, E.
    Havelange, V.
    Leber, B.
    Esteve, J.
    Wang, J.
    Pejsa, V.
    Hajek, R.
    Porkka, K.
    Illes, A.
    Lavie, D.
    Lemoli, R. M.
    Yamamoto, K.
    Yoon, S. -S.
    Jang, J. -H.
    Yeh, S. -P.
    Turgut, M.
    Hong, W. -J.
    Zhou, Y.
    Potluri, J.
    Pratz, K. W.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (07) : 617 - 629
  • [3] How I treat acute myeloid leukemia in the era of new drugs
    DiNardo, Courtney D.
    Wei, Andrew H.
    [J]. BLOOD, 2020, 135 (02) : 85 - 96
  • [4] Infections of Venetoclax-Based Chemotherapy in Acute Myeloid Leukemia: Rationale for Proper Antimicrobial Prophylaxis
    Lee, Raeseok
    Cho, Sung-Yeon
    Lee, Dong-Gun
    Choi, Hyeah
    Park, Silvia
    Cho, Byung-Sik
    Kim, Yoo-Jin
    Kim, Hee-Je
    [J]. CANCERS, 2021, 13 (24)
  • [5] Characterisation of infections in patients with acute myeloid leukaemia receiving venetoclax and a hypomethylating agent
    On, Sandy
    Rath, Carolyn G.
    Lan, Michelle
    Wu, Bobby
    Lau, Kimberly M.
    Cheung, Edna
    Alegria, William
    Young, Rebecca
    Tan, Marisela
    Kim, Carrie
    Phun, Jennifer
    Patel, Nimish
    Mannis, Gabriel
    Logan, Aaron C.
    Kennedy, Vanessa
    Goodman, Aaron
    Taplitz, Randy A.
    Young, Patricia A.
    Wen, Raymond
    Saunders, Ila M.
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2022, 197 (01) : 63 - 70
  • [6] Acute Myeloid Leukemia, Version 2.2021 Featured Updates to the NCCN Guidelines
    Pollyea, Daniel A.
    Bixby, Dale
    Perl, Alexander
    Bhatt, Vijaya Raj
    Altman, Jessica K.
    Appelbaum, Frederick R.
    de Lima, Marcos
    Fathi, Amir T.
    Foran, James M.
    Gojo, Ivana
    Hall, Aric C.
    Jacoby, Meagan
    Lancet, Jeffrey
    Mannis, Gabriel
    Marcucci, Guido
    Martin, Michael G.
    Mims, Alice
    Neff, Jadee
    Nejati, Reza
    Olin, Rebecca
    Percival, Mary-Elizabeth
    Prebet, Thomas
    Przespolewski, Amanda
    Rao, Dinesh
    Ravandi-Kashani, Farhad
    Shami, Paul J.
    Stone, Richard M.
    Strickland, Stephen A.
    Sweet, Kendra
    Vachhani, Pankit
    Wieduwilt, Matthew
    Gregory, Kristina M.
    Ogba, Ndiya
    Tallman, Martin S.
    [J]. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2021, 19 (01): : 17 - 27