Tibial quantitative ultrasound compared to dual-energy X-ray absorptiometry in preterm infants

被引:3
作者
Tarrell, Ariel [1 ]
Grinsell, Matthew [2 ]
Murray, Mary [3 ]
Lewis, Kimberlee Weaver [4 ]
Yoder, Bradley A. [1 ]
Jenkins, Sabrina Malone [1 ]
机构
[1] Univ Utah, Sch Med, Dept Pediat, Div Neonatol, Salt Lake City, UT 84112 USA
[2] Univ Utah, Sch Med, Dept Pediat, Div Nephrol, Salt Lake City, UT USA
[3] Univ Utah, Sch Med, Dept Pediat, Div Endocrinol, Salt Lake City, UT USA
[4] Intermt Healthcare, Women & Newborn Clin Program, Murray, UT USA
关键词
BONE STATUS; TERM; CURVES; HEALTH; BORN;
D O I
10.1038/s41372-022-01588-y
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: The gold standard for diagnosing metabolic bone disease in pediatrics is dual-energy x-ray absorptiometry (DXA). Bone quantitative ultrasound (QUS) has increasing applications. This study compared the relationship of DXA to QUS in preterm infants. DESIGN: Prospective observational study of preterm infants <= 32 weeks gestation or <= 1800 grams at birth. DXA scans measuring bone mineral content (BMC) and tibial QUS scans measuring bone speed of sound (SOS) were obtained near term gestation. RESULTS: 41 infants had bone scans at mean corrected gestation 37.7 +/- 2.1 weeks. BMC and SOS showed weak inverse correlation (R2 0.163, p < 0.01). BMC and SOS correlated with parameters at corrected gestational age at the time of the bone scans (p < 0.05-0.001). SOS correlated with birth gestational age (p < 0.001), not BMC. CONCLUSIONS: A statistically significant weak inverse correlation between DXA and QUS was observed. QUS may have advantages over DXA.
引用
收藏
页码:642 / 646
页数:5
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