Rhodium(II)-Catalyzed N-H Insertions of Carbenes under Mechanochemical Conditions

被引：5

作者：

Biswas, Sourav ^{[1
]}

Bolm, Carsten ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany

来源：

ORGANIC LETTERS | 2024年 / 26卷 / 07期

关键词：

DIAZOACETATES; BONDS; CATALYST; TOOL;

D O I：

10.1021/acs.orglett.4c00216

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Under mechanochemical conditions in a mixer mill, Rh-2(OAc)(4) catalyzes the reaction between aryldiazoesters and anilines to give alpha-amino esters. The process proceeds under mild conditions and is insensitive to air. It is solvent-free and scalable. A broad substrate scope, short reaction times, operational simplicity, and good functional group tolerance are additional salient features of this protocol.

引用

页码：1511 / 1516

页数：6

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