An Excimer Laser-Induced Eruptive Sebaceous Hyperplasia

被引:0
|
作者
Huh, Gyoo [1 ]
Lee, Ga-Young [1 ]
Chae, Seung-Wan [2 ]
Choi, Young-Jun [1 ]
机构
[1] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Dermatol, Sch Med, 29 Saemunan Ro, Seoul 03181, South Korea
[2] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Pathol, Sch Med, Seoul, South Korea
关键词
Excimer laser; Immunosuppressive agents; Sebaceous gland hyperplasia; Ultraviolet therapy; Vitiligo; CAUSE ENLARGEMENT; HAIRLESS MICE; GLAND; AGENTS;
D O I
10.5021/ad.21.020
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Sebaceous hyperplasia (SH) is a benign proliferation of the sebaceous glands. Ultraviolet radiation is known to be the cofactor for the pathogenesis of SH. Frequently reported adverse events of 308-nm excimer laser are erythema, burning or pain, and itching sensation. However, the role of excimer laser as an aetiological factor of SH is rarely reported in the literature. A 59-year-old female presented with several elevated, umbilicated papules on the face. Papular eruption appeared abruptly after 11 weeks of treatment for vitiligo which includes 308-nm excimer laser therapy. The distribution of lesion was associated with the treated area. Total cumulative dose was 3,300 mJ/cm2 over 16 sessions. Histopathologic findings showed enlarged sebaceous glands composed of numerous lobules around a centrally located, widened sebaceous duct. Chronic sun exposure clinically causes SH was proved in the previous animal studies. Thus, we introduce a rare case of eruptive SH in the patient treated with 308-nm excimer laser.
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页码:S268 / S271
页数:4
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