Parainfectious autoimmune encephalitis related to SARS-CoV-2 infection, presented with catatonia

被引:2
作者
Suzgun, Merve Aktan [1 ]
Kizilkilic, Esra Kochan [1 ]
Bostan, Busra Ucar [2 ,3 ]
Tutuncu, Melih [1 ]
Kiziltan, Gunes [1 ]
机构
[1] Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Neurol, Istanbul, Turkiye
[2] Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Psychiat, Istanbul, Turkiye
[3] Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Dept Psychiat, TR-34320 Istanbul, Turkiye
关键词
SARS-CoV-2; catatonia; encephalitis; autoimmunity;
D O I
10.1177/00912174231161393
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective SARS-CoV-2 infection commonly affects both the central and peripheral nervous systems. In this way, different neurological and psychiatric clinical pictures emerge. Whereas the effects of SARS-CoV-2 on neuronal structures in the short and long term are still controversial. Neurological involvement secondary to SARS-CoV-2 is heterogeneous in terms of both clinical presentation and treatment responses and prognosis. Method A case of autoimmune encephalitis developing after SARS-CoV-2 was presented. Results This case was admitted to the clinic with classical catatonia signs and encephalopathy together. The emergence of neuropsychiatric problems after the relief of SARS-CoV-2 symptoms, suggests that this picture was primarily related to immune processes. The presented case showed a good clinical response to symptomatic catatonia treatment and immune-modulatory agents and recovered both physically and cognitively without any sequelae. Conclusion In terms of clinical presentation and treatment response, SARS-CoV-2 infection may create a distinct encephalitic involvement after the infection itself by triggering some defined or not-yet-defined autoimmune pathways.
引用
收藏
页码:403 / 410
页数:8
相关论文
共 25 条
  • [1] Amouri J, 2021, J ACAD CONSULT-LIAIS, V62, P109, DOI 10.1016/j.psym.2020.09.002
  • [2] Autoimmune encephalitis as differential diagnosis of infectious encephalitis
    Armangue, Thais
    Leypoldt, Frank
    Dalmau, Josep
    [J]. CURRENT OPINION IN NEUROLOGY, 2014, 27 (03) : 361 - 368
  • [3] Asgari S, 2022, PROG NEUROL PSYCHIAT, V26, P14
  • [4] Possible Autoimmune Encephalitis with Claustrum Sign in case of Acute SARS-CoV-2 Infection
    Ayatollahi, Parisa
    Tarazi, Apameh
    Wennberg, Richard
    [J]. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2021, 48 (03) : 430 - 432
  • [5] Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Host-Virus Interaction, and Proposed Neurotropic Mechanisms
    Baig, Abdul Mannan
    Khaleeq, Areeba
    Ali, Usman
    Syeda, Hira
    [J]. ACS CHEMICAL NEUROSCIENCE, 2020, 11 (07): : 995 - 998
  • [6] Does SARS-CoV-2 Trigger Stress-Induced Autoimmunity by Molecular Mimicry? A Hypothesis
    Cappello, Francesco
    Gammazza, Antonella Marino
    Dieli, Francesco
    de Macario, Everly Conway
    Macario, Alberto J. L.
    [J]. JOURNAL OF CLINICAL MEDICINE, 2020, 9 (07)
  • [7] CARROLL BT, 1994, J NEUROPSYCH CLIN N, V6, P122
  • [8] Neurological manifestations in COVID-19: a systematic review and meta-analysis
    Chua, Tzy Harn
    Xu, Zheyu
    King, Nicolas Kon Kam
    [J]. BRAIN INJURY, 2020, 34 (12) : 1549 - 1568
  • [9] Malignant catatonia due to anti-NMDA-receptor encephalitis in a 17-year-old girl: Case report
    Consoli A.
    Ronen K.
    An-Gourfinkel I.
    Barbeau M.
    Marra D.
    Costedoat-Chalumeau N.
    Montefiore D.
    Maksud P.
    Bonnot O.
    Didelot A.
    Amoura Z.
    Vidailhet M.
    Cohen D.
    [J]. Child and Adolescent Psychiatry and Mental Health, 5 (1)
  • [10] Antibody-Mediated Encephalitis
    Dalmau, Josep
    Graus, Francesc
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (09) : 840 - 851