Detection of acetylcholinesterase and butyrylcholinesterase in vitro and in vivo using a new fluorescent probe

被引：5
作者：
Tang, Xiaojie [1 ]
Zhang, Yuan [1 ]
Wang, Qiuyue [1 ]
Li, Zhao [1 ]
Zhang, Chengxiao [1 ]
机构：
[1] Shaanxi Normal Univ, Coll Food Engn & Nutr Sci, Shaanxi Engn Lab Food Green Proc & Safety Control, Xian 710062, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 15期
关键词：
CHOLINESTERASE ACTIVITY; CARBON-MONOXIDE; ZEBRAFISH; BIOSENSOR; DESIGN; CELLS;
D O I：
10.1039/d3cc06055a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new fluorescence probe OHPD that could specifically identify acetylcholinesterase/butyrylcholinesterase has been developed and successfully applied to imaging in vivo. Probe OHPD shows significant color change, high selectivity, high sensitivity, and low detection limit for the detection of cholinesterase. Moreover, the real-time imaging in situ indicated that endogenous cholinesterase was mainly present in the yolk sac of zebrafish.
引用
收藏
页码：2082 / 2085
页数：4
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