Citrus Limon Has the Potential to Reduce Oxidative Stress and Inflammation After Physical Activity/Exercise: Systematic Review

This study aims to analyze and highlight the potential of citrus limon in reducing inflammation and oxydatif stress after physical activity/exercise. This study uses a systematic review method by searching various journal databases such as Scopus, Web of Science, Pubmed, and Embase. The inclusion criteria in this study were articles published within the last 5 years and articles discussing Limon, Inflammation, Free Radicals, and physical exercise. Exclusion criteria in this study were articles published in disreputable journals. A total of 1665 articles from Scopus, Web of Science Pubmed and Embase databases were identified. A total of 7 articles that met the inclusion criteria were selected and analyzed for this systematic review. For standard operations, this study follows the Preferred Reporting Items for Systematic review and Meta-Analyses (PRISMA) assessment. The results of this systematic research review report that the flavanoid content found in citrus limon has anti-oxidant properties that can reduce oxidative stress. Furthermore, the anti-inflammatory properties of citrus limon can reduce uncontrolled inflammation due to physical activity and intense exercise. In this case, citrus limon works by inhibiting inflammation through NF-kB signaling and reducing inflammation by suppressing the secretion of pro-inflammatory cytokines such as TNF-a. Reducing inflammation can potentially reduce the intensity of muscle pain. We recommend that citrus limon be used in individuals to reduce oxidative stress and inflammation caused by physical activity and intense exercise.