Diastereoselective Synthesis of 3-[2-Chloro(bromo)phenyl]-2-methyl-2-[(prop-2-yn-1-yl)oxy]oxiranes and 5-[3-Chloro(bromo)phenyl]-2,2,4-trimethyl-4-[(prop-2-yn-1-yl)]-1,3-dioxolane

被引：0

作者：

Talybov, G. M. ^{[1
]}

Akhmedova, N. Ya. ^{[1
]}

机构：

[1] Azerbaijan Tech Univ, Baku 1073, Azerbaijan

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 59卷 / 05期

关键词：

halogenated benzaldehydes; 3-(1-chloroethoxy)prop-1-yne; unsaturated ethers of 2-hydroxyoxirane; substituted; 1; 3-dioxolanes;

D O I：

10.1134/S1070428023050032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of halogen-substituted benzaldehydes with 3-(1-chloroethoxy)prop-1-yne leads to the formation of unsaturated ethers derived from 2-hydroxyoxirane. The formation of the latter was confirmed by its reaction with acetone in the presence of BF3 & BULL;Et2O to give substituted 1,3-dioxolanes.

引用

页码：764 / 768

页数：5

共 7 条

[1] A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo [J].