Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy

被引:35
作者
Omidian, Hossein [1 ]
Chowdhury, Sumana Dey [1 ]
机构
[1] Nova Southeastern Univ, Barry & Judy Silverman Coll Pharm, Ft Lauderdale, FL 33328 USA
关键词
injectable hydrogel nanocomposites; biomedical applications; controlled release; tissue engineering; therapeutic outcomes; IN-GEL SYSTEM; CONTROLLED-RELEASE; BONE REGENERATION; DRUG-DELIVERY; NANOCOMPOSITE HYDROGEL; NANO-HYDROXYAPATITE; PHYSICAL-PROPERTIES; FORMING HYDROGEL; ALGINATE; CHITOSAN;
D O I
10.3390/gels9070533
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Injectable hydrogels have gained popularity for their controlled release, targeted delivery, and enhanced mechanical properties. They hold promise in cardiac regeneration, joint diseases, postoperative analgesia, and ocular disorder treatment. Hydrogels enriched with nano-hydroxyapatite show potential in bone regeneration, addressing challenges of bone defects, osteoporosis, and tumor-associated regeneration. In wound management and cancer therapy, they enable controlled release, accelerated wound closure, and targeted drug delivery. Injectable hydrogels also find applications in ischemic brain injury, tissue regeneration, cardiovascular diseases, and personalized cancer immunotherapy. This manuscript highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research. Moreover, it includes a perspective section that explores future prospects, emphasizes interdisciplinary collaboration, and underscores the promising future potential of injectable hydrogel nanocomposites in biomedical research and applications.
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页数:37
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