Interaction of different lasers beams with synthesized H2Ti3O7 nanotubes: toward photodynamic therapy

The interaction of laser beams with metal oxide nanoparticles can be proposed for water remediation and cancer treatment. In this paper, H2Ti3O7 nanotubes (NTs) were synthesized by anodization technique and characterized using UV-visible, Raman scattering and FTIR and spectroscopies, field emission scanning and transmission electron microscopy, zeta potential, thermal analysis, and X-ray diffraction. The results declare that monoclinic hydrogen titanium oxide with a mean crystallite size of 16.0 nm is formed. The H2Ti3O7 NTs also have an average outer diameter and shell thickness of 34.0 nm and 1.69 nm, respectively. Furthermore, the NTs have considerable thermal stability and high colloidal stability with a negative surface charge value of - 39.6 mV. Additionally, the interactions of different laser lights with H2Ti3O7 NTs in the vicinity of lung and prostate cancer as two of the first frequent malignancy worldwide in male cancer with a significant increasing trend are in vitro investigated. The effects of various concentrations of bare H2Ti3O7 NTs at different incubation times in the presence and absence of laser light are investigated to estimate the effectiveness of the photodynamic therapy. Also, different laser wavelengths, laser intensities, and exposure times are applied to treat lung (A549 cells) and prostate (LNCap cells) treatment. The results indicated that H2Ti3O7 NTs can be an excellent candidate for the treatment of lung and prostate cancers and the reasons for the success of the treatment in dark and irradiated conditions are described in the paper. [GRAPHICS.]