Canine Atopic Dermatitis: Prevalence, Impact, and Management Strategies

被引：13

作者：

Drechsler, Yvonne ^{[1
,3
]}

Dong, Charli ^{[2
]}

Clark, David E. ^{[1
]}

Kaur, Gagandeep ^{[1
]}

机构：

[1] Western Univ Hlth Sci, Coll Vet Med, Pomona, CA USA

[2] Anim Dermatol Clin, Pasadena, CA USA

[3] Western Univ Hlth Sci, Coll Vet Med, 309 E Second St, Pomona, CA 91711 USA

来源：

VETERINARY MEDICINE-RESEARCH AND REPORTS | 2024年 / 15卷

关键词：

immunopathology; topical therapies; systemic therapies; pruritus; immune therapies; alarmins; THYMIC STROMAL LYMPHOPOIETIN; CLIENT-OWNED DOGS; ACVD TASK-FORCE; WET WRAP THERAPY; TACROLIMUS OINTMENT; SKIN MICROBIOME; CYCLOSPORINE-A; ESSENTIAL OILS; HEALTHY DOGS; FATTY-ACIDS;

D O I：

10.2147/VMRR.S412570

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Atopic dermatitis (AD) is a common inflammatory and pruritic allergic skin disease in humans and dogs worldwide. The pathogenesis of AD is multifactorial, immunologically complex, and may involve genetic factors, epidermal barrier dysfunction, microbiome changes, immune dysregulation, and allergic sensitization. Across species, prevalence of AD is on the rise. At present, there is no cure for canine AD (CAD). The treatment for CAD is multifaceted and aimed at controlling the pruritus, associated inflammation, and infections, repairing the skin barrier function, and dietary management. This review presents data on prevalence, impact, and complex immunological interactions in AD with a focus on subsequent management of the disease in the canine population. A multimodal approach for management of CAD to address varying clinical signs and responses to therapies is discussed.

引用

页码：15 / 29

页数：15

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