A new coumarin glucoside from Angelica pubescens

被引：3
|
作者：
Zhao, Han-tao [1 ]
Yang, Jun [1 ]
Chen, Qian-feng [1 ]
机构：
[1] Southwest Univ, Coll Pharmaceut Sci, Chongqing, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2025年 / 39卷 / 03期
关键词：
Chemical constituents; anti-inflammatory activity; RAW; 264.7; cells; nitric oxide; GLYCOSIDES;
D O I：
10.1080/14786419.2023.2275265
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new coumarin glucoside named angelol A-3'-beta-D-glucoside and four known compounds (2-5) were isolated from the root of Angelica pubescens. Their chemical structures were elucidated by extensive spectroscopic methods involving HR-ESI-MS, 1D and 2D NMR. The absolute configuration of compound 1 was confirmed by the CD experiment. All compounds were tested for nitric oxide (NO) inhibitory activity in vitro. The results showed that all compounds exhibited weak to moderate inhibition activities of NO production except compound 5.
引用
收藏
页码：526 / 530
页数：5
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