A practical review of watch-and-wait approach in rectal cancer

被引:14
作者
Byun, Hwa Kyung [1 ]
Koom, Woong Sub [1 ]
机构
[1] Yonsei Univ, Yonsei Canc Ctr, Dept Radiat Oncol, Coll Med, 50-1 Yonsei Ro, Seoul 03722, South Korea
基金
新加坡国家研究基金会;
关键词
Rectal neoplasms; Watch and wait; Non-operative management; CLINICAL COMPLETE RESPONSE; TOTAL MESORECTAL EXCISION; LONG-TERM-OUTCOMES; PREOPERATIVE CHEMORADIOTHERAPY; NEOADJUVANT CHEMORADIATION; NONOPERATIVE MANAGEMENT; OPEN-LABEL; CHEMOTHERAPY; MULTICENTER; RESECTION;
D O I
10.3857/roj.2023.00038
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Rectal resection surgery after neoadjuvant treatment has been the mainstay treatment of locally advanced rectal cancer. However, functional outcomes and quality of life after radical resection of the rectum remain suboptimal. The excellent oncologic outcomes in patients who achieved pathologic complete response after neoadjuvant treatment questioned the need for radical surgery. The watchand-wait approach is a noninvasive therapeutic alternative for organ preservation and avoiding operative morbidity. In the watch-and-wait approach, patients with locally advanced rectal cancer who achieve excellent clinical response after neoadjuvant treatment undergo active surveillance rather than rectal cancer surgery. In this practical review, we summarized the main results of studies on the watch-and-wait approach and provided a practical method for implementing the watch-and-wait approach.
引用
收藏
页码:4 / 11
页数:8
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