Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease

被引：0

作者：

Hildenbrand, Aimee K. ^{[1
,2
,3
,8
]}

Kidwell, Katherine M. ^{[4
]}

Mcgrady, Meghan E. ^{[5
,6
]}

Mara, Constance A. ^{[5
,6
]}

Quinn, Charles ^{[6
,7
]}

Crosby, Lori E. ^{[5
,6
]}

机构：

[1] Nemours Childrens Hlth, Ctr Healthcare Delivery Sci, Wilmington, DE USA

[2] Nemours Childrens Hosp Delaware, Div Behav Hlth, Wilmington, DE USA

[3] Thomas Jefferson Univ, Sidney Kimmel Med Coll, Dept Pediat, Philadelphia, PA USA

[4] Syracuse Univ, Dept Psychol, Syracuse, NY USA

[5] Cincinnati Childrens Hosp Med Ctr, Div Behav Med & Clin Psychol, Cincinnati, OH USA

[6] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA

[7] Cincinnati Childrens Hosp Med Ctr, Div Hematol, Cincinnati, OH USA

[8] Nemours Ctr Healthcare Delivery Sci, 1600 Rockland Rd,RC 1,Suite 160, Wilmington, DE 19803 USA

来源：

PATIENT PREFERENCE AND ADHERENCE | 2023年 / 17卷

基金：

美国国家卫生研究院;

关键词：

adherence; MEMS; medicine; sickle cell anemia; PEDIATRIC-PATIENTS; YOUNG-ADULTS; FOLLOW-UP; ADHERENCE; CHILDREN; HYDROXYUREA;

D O I：

10.2147/PPA.S431595

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose: To examine the feasibility of using MEMS (R) bottles to assess adherence among adolescents and emerging adults with sickle cell disease. Patients and Methods: Eighteen non-Hispanic Black participants with HbSS (M = 17.8 years; 61% male) were given a MEMS (R) bottle to store hydroxyurea (n = 14) or deferasirox (n = 4). Results: One hundred percent initiated MEMS (R) use and 61% sustained use through the 18-week study; at follow-up, only 11% returned their bottle on time. Barriers to MEMS (R) use included medication changes and transition to adult care; facilitators included tip sheets and reminders. Conclusion: While MEMS (R) is acceptable to this population, ensuring sustained use and timely provision of bottles will require additional supports.

引用

页码：3167 / 3171

页数：5

共 15 条

[1]

Arnett J.J., 2007, Adolescence and emerging adulthood: A cultural approach

[2] Technology Access and Smartphone App Preferences for Medication Adherence in Adolescents and Young Adults With Sickle Cell Disease [J].

Badawy, Sherif M. ;

Thompson, Alexis A. ;

Liem, Robert I. .

PEDIATRIC BLOOD & CANCER, 2016, 63 (05) :848-852

[3] The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease [J].

Ballas, Samir K. .

MEDITERRANEAN JOURNAL OF HEMATOLOGY AND INFECTIOUS DISEASES, 2020, 12

[4] Trying to improve compliance with prophylactic penicillin therapy in children with sickle cell disease [J].

Berkovitch, M ;

Papadouris, D ;

Shaw, D ;

Onuaha, N ;

Dias, C ;

Olivieri, NF .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1998, 45 (06) :605-607

[5] Pilot of the Chronic Disease Self-Management Program for Adolescents and Young Adults With Sickle Cell Disease [J].

Crosby, Lori E. ;

Joffe, Naomi E. ;

Peugh, James ;

Ware, Russell E. ;

Britto, Maria T. .

JOURNAL OF ADOLESCENT HEALTH, 2017, 60 (01) :120-123

[6] How much loss to follow-up is acceptable in long-term randomised trials and prospective studies? [J].

Fewtrell, Mary S. ;

Kennedy, Kathy ;

Singhal, Atul ;

Martin, Richard M. ;

Ness, Andy ;

Hadders-Algra, Mijna ;

Koletzko, Berthold ;

Lucas, Alan .

ARCHIVES OF DISEASE IN CHILDHOOD, 2008, 93 (06) :458-461

[7] Sickle cell disease related mortality in the United States (1999-2009) [J].

Hamideh, Dima ;

Alvarez, Ofelia .

PEDIATRIC BLOOD & CANCER, 2013, 60 (09) :1482-1486

[8] Adherence to hydroxyurea medication by children with sickle cell disease (SCD) using an electronic device: a feasibility study [J].

Inoue, Susumu ;

Kodjebacheva, Gergana ;

Scherrer, Tammy ;

Rice, Gary ;

Grigorian, Matthew ;

Blankenship, Jeremy ;

Onwuzurike, Nkechi .

INTERNATIONAL JOURNAL OF HEMATOLOGY, 2016, 104 (02) :200-207

[9] Loss to follow-up in cohort studies: How much is too much? [J].

Kristman V. ;

Manno M. ;

Côté P. .

European Journal of Epidemiology, 2004, 19 (8) :751-760

[10] Systematic and Meta-Analytic Review: Medication Adherence Among Pediatric Patients With Sickle Cell Disease [J].

Loiselle, Kristin ;

Lee, Jennifer L. ;

Szulczewski, Lauren ;

Drake, Sarah ;

Crosby, Lori E. ;

Pai, Ahna L. H. .

JOURNAL OF PEDIATRIC PSYCHOLOGY, 2016, 41 (04) :406-418

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