Unintentional pediatric poisonings before and during the COVID-19 pandemic: A population-based study

被引：2
作者：
Myran, Daniel T. [1 ,2 ,3 ,4 ,9 ]
Gaudreault, Adrienne [1 ]
Mccarthy, Stephen D. S. [1 ]
Pugliese, Michael [3 ]
Tanuseputro, Peter [1 ,2 ,3 ,4 ]
Finkelstein, Yaron [5 ,6 ,7 ,8 ]
机构：
[1] Ottawa Hosp Res Inst, Clin Epidemiol Program, Ottawa, ON, Canada
[2] Univ Ottawa, Dept Family Med, Ottawa, ON, Canada
[3] Ottawa Hosp Res Inst, ICES uOttawa, Ottawa, ON, Canada
[4] Bruyere Res Inst, Ottawa, ON, Canada
[5] Hosp Sick Children, Div Pediat Emergency Med, Toronto, ON M5G 1X8, Canada
[6] Hosp Sick Children, Div Clin Pharmacol & Toxicol, Toronto, ON, Canada
[7] Univ Toronto, Dept Pediat, Toronto, ON, Canada
[8] Univ Toronto, Dept Pharmacol & Toxicol, Toronto, ON, Canada
[9] Ottawa Hosp Res Inst, 1053 Carling Ave, POB 693, Ottawa, ON K1Y 4E9, Canada
来源：
AMERICAN JOURNAL OF EMERGENCY MEDICINE | 2024年 / 76卷
基金：
加拿大健康研究院;
关键词：
Available online xxxx; COVID-19; Poisoning; Children; Pediatrics; cannabis; Legalization;
D O I：
10.1016/j.ajem.2023.11.042
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Objectives: The impact of coronavirus disease 2019 (COVID-19) on unintentional pediatric poisonings is unclear. We examined changes in emergency department (ED) visits and hospitalizations for poisonings before and during the COVID-19 pandemic. We compared changes in cannabis vs non-cannabis poisoning events given the recent legalization of cannabis in October 2018 and cannabis edibles in January 2020.Study design: Interrupted time-series (ITS) analyses of changes in population-level ED visits and hospitalizations for poisonings in children aged 0-9 years in Ontario, Canada (annual population of 1.4 million children), over two time periods: pre-pandemic (January 2010-March 2020) and pandemic (April 2020-December 2021). Results: Overall, there were 28,292 ED visits and 2641 hospitalizations for unintentional poisonings. During the pandemic, poisonings per 100,000 person-years decreased by 14.6% for ED visits (40.15 pre-vs. 34.29 during) and increased by 35.9% for hospitalizations (3.48 pre-vs. 4.73 during). ED visits dropped immediately (Incidence Rate Ratio [IRR], 0.76; 95% CI, 0.70-0.82) at the onset of the pandemic, followed by a gradual return to baseline (quarterly change, IRR 1.04, 95%CI 1.03-1.06), while hospitalizations had an immediate increase (IRR 1.34; 95% CI, 1.08-1.66) and no gradual change. The only increase in poisonings was for cannabis which had a 10.7 -fold for ED visits (0.45 to 4.83 per 100,000 person-years) and a 12.1-fold increase for hospitalizations (0.16 to 1.91 per 100,000 person-years). Excluding cannabis, there was no overall increase in poisoning hospitalizations. Conclusions: The COVID-19 pandemic was not associated with increases in any type of unintentional pediatric poisonings, with the exception of cannabis poisonings. Increased cannabis poisonings may be explained by the legalization of non-medical cannabis edibles in Canada in January 2020.(c) 2023 Elsevier Inc. All rights reserved.
引用
收藏
页码：185 / 192
页数：8
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