Functional and Quality of Life Outcomes After TAVR in Patients With Low Gradient Aortic Stenosis

被引：1

作者：

Chiang, Caleb ^{[1
]}

Brandon, Margaret ^{[1
,2
]}

Danley, Kelsey ^{[1
]}

Luo, Shengyuan ^{[1
]}

Honasoge, Akilesh ^{[1
]}

Derbas, Laith A. ^{[1
]}

Jolly, Neeraj ^{[1
]}

Collado, Fareed ^{[1
]}

Kavinsky, Clifford J. ^{[1
]}

Suradi, Hussam S. ^{[1
]}

机构：

[1] Rush Univ, Med Ctr, Chicago, IL USA

[2] Rush Univ, Dept Neurol, Med Ctr, 1717 W Congress Pkwy, 10th Fl, Chicago, IL 60612 USA

来源：

CURRENT PROBLEMS IN CARDIOLOGY | 2024年 / 49卷 / 01期

关键词：

VALVE-REPLACEMENT; SYMPTOMATIC PATIENTS; NORMAL FLOW; IMPLANTATION; PREFERENCES; PREDICTORS; THERAPY; BENEFIT; IMPACT; TRIAL;

D O I：

10.1016/j.cpcardiol.2023.101941

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Severe aortic stenosis is a common valvular heart disease associated with significant mortality and morbidity. Transcatheter aortic valve replacement (TAVR) is an effective treatment for this condition. Less data is available regarding functional and quality of-life outcomes in patients with severe, low-gradient aortic stenosis following TAVR. This single-center, retrospective study compared changes in New York Heart Association (NYHA) class and Kansas City Cardiomyopathy Questionnaire (KCCQ) scores at 30 days and 1 year in patients with 3 variants of severe, low-gradient aortic stenosis following TAVR. Secondary outcomes included 1-year major adverse cardiovascular event. A total of 170 patients were included. All 3 low-gradient variants had significant improvement in NYHA class and KCCQ overall scores at 30 days and 1 year. There were no significant differences in KCCQ overall scores between the 3 groups and no significant differences in secondary outcomes. Patients with low-gradient aortic stenosis experienced significant improvements in functional and quality-of-life outcomes following TAVR.

引用

页数：14

共 24 条

[1] Changes in quality of life in patients with low-flow aortic stenosis undergoing transcatheter aortic valve replacement [J].

Ahmed, Aisha ;

Alsidawi, Said ;

Bae, Richard ;

Cavalcante, Joao ;

Fukui, Miho ;

Gossl, Mario ;

Sorajja, Paul ;

Garcia, Santiago .

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 2020, 96 (04) :972-978

[2] Comparison of Benefit of Transcatheter Aortic Valve Implantation in Patients With Low Gradient Versus High Gradient Aortic Stenosis and Left Ventricular Dysfunction [J].

Amer, Mostafa R. ;

Mosleh, Wassim ;

Memon, Sarfaraz ;

Joshi, Saurabh ;

Sullivan, Bethany ;

Sharkawi, Musa ;

Mather, Jeffrey F. ;

Kiernan, Francis J. ;

McMahon, Sean ;

Duvall, W. Lane ;

McKay, Raymond G. .

AMERICAN JOURNAL OF CARDIOLOGY, 2020, 125 (10) :1543-1549

[3] Quality-of-Life Outcomes After Transcatheter Aortic Valve Replacement in an Unselected Population A Report From the STS/ACC Transcatheter Valve Therapy Registry [J].

Arnold, Suzanne V. ;

Spertus, John A. ;

Vemulapalli, Sreekanth ;

Li, Zhuokai ;

Matsouaka, Roland A. ;

Baron, Suzanne J. ;

Vora, Amit N. ;

Mack, Michael J. ;

Reynolds, Matthew R. ;

Rumsfeld, John S. ;

Cohen, David J. .

JAMA CARDIOLOGY, 2017, 2 (04) :409-416

[4] Use of the Kansas City Cardiomyopathy Questionnaire for Monitoring Health Status in Patients With Aortic Stenosis [J].

Arnold, Suzanne V. ;

Spertus, John A. ;

Lei, Yang ;

Allen, Keith B. ;

Chhatriwalla, Adnan K. ;

Leon, Martin B. ;

Smith, Craig R. ;

Reynolds, Matthew R. ;

Webb, John G. ;

Svensson, Lars G. ;

Cohen, David J. .

CIRCULATION-HEART FAILURE, 2013, 6 (01) :61-+

[5] Correlates and Causes of Death in Patients With Severe Symptomatic Aortic Stenosis Who Are Not Eligible to Participate in a Clinical Trial of Transcatheter Aortic Valve Implantation [J].

Ben-Dor, Itsik ;

Pichard, Augusto D. ;

Gonzalez, Manuel A. ;

Weissman, Gaby ;

Li, Yanlin ;

Goldstein, Steven A. ;

Okubagzi, Petros ;

Syed, Asmir I. ;

Maluenda, Gabriel ;

Collins, Sara D. ;

Delhaye, Cedric ;

Wakabayashi, Kohei ;

Gaglia, Michael A., Jr. ;

Torguson, Rebecca ;

Xue, Zhenyi ;

Satler, Lowell F. ;

Suddath, William O. ;

Kent, Kenneth M. ;

Lindsay, Joseph ;

Waksman, Ron .

CIRCULATION, 2010, 122 (11) :S37-S42

[6] Discordant Grading of Aortic Stenosis Severity Echocardiographic Predictors of Survival Benefit Associated With Aortic Valve Replacement [J].

Berthelot-Richer, Maxime ;

Pibarot, Philippe ;

Capoulade, Romain ;

Dumesnil, Jean G. ;

Dahou, Abdellaziz ;

Thebault, Christophe ;

Le Ven, Florent ;

Clavel, Marie-Annick .

JACC-CARDIOVASCULAR IMAGING, 2016, 9 (07) :797-805

[7] Systemic Hypertension in Low-Gradient Severe Aortic Stenosis With Preserved Ejection Fraction [J].

Eleid, Mackram F. ;

Nishimura, Rick A. ;

Sorajja, Paul ;

Borlaug, Barry A. .

CIRCULATION, 2013, 128 (12) :1349-1353

[8] Impact of Arterial Blood Pressure on Ultrasound Hemodynamic Assessment of Aortic Valve Stenosis Severity [J].

Hayek, Ahmad ;

Derimay, Francois ;

Green, Lisa ;

Rosset, Marion ;

Thibault, Helene ;

Rioufol, Gilles ;

Finet, Gerard .

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2020, 33 (11) :1324-1333

[9] Predictors of Mortality and Outcomes of Therapy in Low-Flow Severe Aortic Stenosis: A Placement of Aortic Transcatheter Valves (PARTNER) Trial Analysis [J].

Herrmann, Howard C. ;

Pibarot, Philippe ;

Hueter, Irene ;

Gertz, Zachary M. ;

Stewart, William J. ;

Kapadia, Samir ;

Tuzcu, E. Murat ;

Babaliaros, Vasilis ;

Thourani, Vinod ;

Szeto, Wilson Y. ;

Bavaria, Joseph E. ;

Kodali, Susheel ;

Hahn, Rebecca T. ;

Williams, Mathew ;

Miller, D. Craig ;

Douglas, Pamela S. ;

Leon, Martin B. .

CIRCULATION, 2013, 127 (23) :2316-2326

[10] Outcome of Patients With Low-Gradient "Severe" Aortic Stenosis and Preserved Ejection Fraction [J].

Jander, Nikolaus ;

Minners, Jan ;

Holme, Ingar ;

Gerdts, Eva ;

Boman, Kurt ;

Brudi, Philippe ;

Chambers, John B. ;

Egstrup, Kenneth ;

Kesaniemi, Y. Antero ;

Malbecq, William ;

Nienaber, Christoph A. ;

Ray, Simon ;

Rossebo, Anne ;

Pedersen, Terje R. ;

Skjaerpe, Terje ;

Willenheimer, Ronnie ;

Wachtell, Kristian ;

Neumann, Franz-Josef ;

Gohlke-Baerwolf, Christa .

CIRCULATION, 2011, 123 (08) :887-895

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