Optimizing the Immunogenicity of HIV Vaccines by Adjuvants - NIAID Workshop Report

被引:0
|
作者
Singh, Anjali [1 ]
Boggiano, Cesar [1 ]
Eller, Michael A. [1 ]
Maciel Jr, Milton [1 ]
Marovich, Mary A. [1 ]
Mehra, Vijay L. [1 ]
Mo, Annie X. [2 ]
Singleton, Kentner L. [3 ]
Leitner, Wolfgang W. [3 ]
机构
[1] NIAID, Div AIDS, NIH, Bethesda, MD USA
[2] NIAID, Div Microbiol & Infect Dis, NIH, Bethesda, MD USA
[3] NIAID, Div Allergy Immunol & Transplantat, NIH, Bethesda, MD 20892 USA
关键词
HIV; Adjuvant; Vaccine; Broadly neutralizing antibody; Immunogenicity; DELTA INULIN; ENVELOPE;
D O I
10.1016/j.vaccine.2023.06.029
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
This report summarizes the highlights of a workshop convened by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), on April 4-5, 2022, to provide a discussion forum for sharing insights on the current status, key challenges, and next steps to advance the current landscape of promising adjuvants in preclinical and clinical human immunodeficiency virus (HIV) vaccine studies. A key goal was to solicit and share recommendations on scientific, regulatory, and operational guidelines for bridging the gaps in rational selection, access, and formulation of clinically relevant adjuvants for HIV vaccine candidates. The NIAID Vaccine Adjuvant Program working group remains committed to accentuate promising adjuvants and nurturing collaborations between adjuvant and HIV vaccine developers.
引用
收藏
页码:4439 / 4446
页数:8
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