Transition-Metal-Free Synthesis of Polyfluoro-Polyarylmethanes via Direct Cross-Coupling of Polyfluoroarenes and Benzyl Chlorides

被引：1
|
作者：
Zhou, Yu [1 ,2 ]
Hu, Dandan [1 ]
Zhang, Yuting [1 ]
Cen, Qiyou [1 ]
Dong, Zhi-Bing [2 ]
Zhang, Jun-Qi [1 ]
Ren, Hongjun [1 ,2 ,3 ]
机构：
[1] Taizhou Univ, Adv Res Inst, Dept Chem, Jiaojiang 318000, Peoples R China
[2] Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430205, Peoples R China
[3] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453000, Peoples R China
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2023年 / 29卷 / 19期
基金：
中国国家自然科学基金;
关键词：
cross-coupling; Grignard reagent; magnesium; polyfluoro-polyarylmethanes; transition metal-free; CATALYZED C(SP(3))-H ARYLATION; PARA-QUINONE METHIDES; C-H BOND; ENANTIOSELECTIVE SYNTHESIS; SEQUENTIAL ARYLATION; ASYMMETRIC-SYNTHESIS; ORGANIC FRAMEWORKS; TRIARYLMETHANES; EFFICIENT; SECONDARY;
D O I：
10.1002/chem.202203427
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The transition-metal-free direct cross-coupling between polyfluoroarenes and benzyl chlorides is reported. In this strategy, a variety of polyfluoro di-, tri- and tetra-arylmethanes was efficiently prepared with good to excellent yields in the presence of Mg turnings via a one-pot procedure. Significantly, this method provides a general approach for the synthesis of polyfluorinated polyarylmethanes.
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页数：6
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