Transition-Metal-Free Synthesis of Polyfluoro-Polyarylmethanes via Direct Cross-Coupling of Polyfluoroarenes and Benzyl Chlorides

被引：1

作者：

Zhou, Yu ^{[1
,2
]}

Hu, Dandan ^{[1
]}

Zhang, Yuting ^{[1
]}

Cen, Qiyou ^{[1
]}

Dong, Zhi-Bing ^{[2
]}

Zhang, Jun-Qi ^{[1
]}

Ren, Hongjun ^{[1
,2
,3
]}

机构：

[1] Taizhou Univ, Adv Res Inst, Dept Chem, Jiaojiang 318000, Peoples R China

[2] Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430205, Peoples R China

[3] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453000, Peoples R China

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2023年 / 29卷 / 19期

基金：

中国国家自然科学基金;

关键词：

cross-coupling; Grignard reagent; magnesium; polyfluoro-polyarylmethanes; transition metal-free; CATALYZED C(SP(3))-H ARYLATION; PARA-QUINONE METHIDES; C-H BOND; ENANTIOSELECTIVE SYNTHESIS; SEQUENTIAL ARYLATION; ASYMMETRIC-SYNTHESIS; ORGANIC FRAMEWORKS; TRIARYLMETHANES; EFFICIENT; SECONDARY;

D O I：

10.1002/chem.202203427

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The transition-metal-free direct cross-coupling between polyfluoroarenes and benzyl chlorides is reported. In this strategy, a variety of polyfluoro di-, tri- and tetra-arylmethanes was efficiently prepared with good to excellent yields in the presence of Mg turnings via a one-pot procedure. Significantly, this method provides a general approach for the synthesis of polyfluorinated polyarylmethanes.

引用

页数：6

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