Objective: To describe the surgical technique and report the early outcomes of the transvesical (TV) approach to single-port (SP) robot-assisted radical prostatectomy.Methods: All procedures were performed at a single center by one surgeon. We identified the first 100 consecutive patients with clinically localized prostate cancer that underwent SP TV robot-assisted radical prostatectomy using the da Vinci SP robotic surgical system. Data were collected prospectively and analyzed with descriptive statistics. The primary outcomes assessed were postoperative urinary continence, rate of biochemical recurrence, and sexual function.Results: All procedures were performed without extra ports or conversion. The median age was 62.1 years and 49.0% of the patients had abdominal surgery history. The preoperative median prostate-specific antigen value and prostate volume were 5.0 ng/mL and 33.0 mL, respectively. There were no intraoperative complications. The median operative time and estimated blood loss were 212.5 min and 100.0 mL, respectively. A total of 92.0% of patients were discharged within 24.0 h, with an overall median length of stay of 5.6 h. Only 4.0% of patients required opioid prescriptions at discharge. The median Foley catheter duration was 3 days. Positive margins were present in 15.0% of cases. Median follow-up was 10.4 months. Continence rate was immediate after Foley removal in 49.0% of cases, 65.0% at 2 weeks, 77.4% at 6 weeks, 94.1% at 6 months, and 98.9% at 1 year. One case of biochemical recurrence (1.0%) was noted 3 months after surgery. Conclusion: The SP TV approach for radical prostatectomy cases is a safe and feasible technique for patients with clinically localized prostate cancer. This technique offers advantages of short hospital stay, minimal narcotic use postoperatively, and promising early return of urinary continence, without compromising oncologic outcomes. 2023 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Jiang, Chun
Huang, Jian
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Huang, Jian
Lin, Tianxin
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Lin, Tianxin
Xu, Kewei
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Xu, Kewei
Han, Jinli
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Han, Jinli
Huang, Hai
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Huang, Hai
Xie, Wenlian
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Xie, Wenlian
Yao, Yousheng
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Yao, Yousheng
Guo, Zhenghui
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
Guo, Zhenghui
Bi, Liangkuan
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Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R ChinaSun Yat Sen Univ, Sun Yat Sen Mem Hosp, Dept Urol, Guangzhou 510120, Guangdong, Peoples R China
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Department of Urology, Hackensack University Medical Center, Hackensack, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Sonam Saxena
Mubashir S. Billah
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Department of Urology, Hackensack University Medical Center, Hackensack, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Mubashir S. Billah
Angelo Cadiente
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Hackensack Meridian School of Medicine, Nutley, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Angelo Cadiente
Catherine Implicito
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Hackensack Meridian School of Medicine, Nutley, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Catherine Implicito
Daniel Thiemann
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Hackensack Meridian School of Medicine, Nutley, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Daniel Thiemann
Sarah Brink
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Department of Urology, Hackensack University Medical Center, Hackensack, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Sarah Brink
Aisha Kourouma
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Department of Urology, Hackensack University Medical Center, Hackensack, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Aisha Kourouma
Ruth Sanchez de la Rosa
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Department of Urology, Hackensack University Medical Center, Hackensack, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Ruth Sanchez de la Rosa
Michael D. Stifelman
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Hackensack Meridian School of Medicine, Nutley, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ
Michael D. Stifelman
Mutahar Ahmed
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Hackensack Meridian School of Medicine, Nutley, NJDepartment of Urology, Hackensack University Medical Center, Hackensack, NJ