Visible light-induced radical cascade acylmethylation/cyclization of 2-(allyloxy) arylaldehydes with α-bromo ketones: access to cyclic 1,5-dicarbonyl-containing chroman-4-one skeletons

被引：7

作者：

Huang, Xiao-Hong ^{[1
]}

Liu, Feng-Lin ^{[1
]}

Fu, Ting-Feng ^{[1
]}

Hu, Xiao ^{[1
]}

Wang, Ya-Yu ^{[1
]}

Liu, Bo ^{[1
]}

Teng, Ming-Yu ^{[1
]}

Huang, Guo-Li ^{[1
]}

机构：

[1] Yunnan Normal Univ, Sch Chem & Chem Engn, Kunming 650050, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2023年 / 21卷 / 33期

关键词：

DERIVATIVES; CYCLIZATION; INHIBITORS;

D O I：

10.1039/d3ob01101a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel photocatalytic protocol for effective and efficient synthesis of cyclic 1,5-diketones containing chroman-4-one skeletons in moderate to good yields via radical cascade acylmethylation/cyclization of 2-(allyloxy)arylaldehydes with a-bromo ketones has been described. This reaction features a broad substrate scope, good functional group tolerance, and metal- and oxidant-free conditions. An acylmethyl radical-triggered cascade cyclization was involved.

引用

页码：6772 / 6777

页数：6

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