Special Populations Treatment-Resistant Depression in Children and Adolescents

被引：8

作者：

Ayvaci, Emine Rabia ^{[1
]}

Croarkin, Paul E. ^{[2
]}

机构：

[1] UT Southwestern Med Ctr, Dept Psychiat, 6300 Harry Hines Blvd, Dallas, TX 75235 USA

[2] Mayo Clin, Dept Psychiat & Psychol, 200 First St Southwest, Rochester, MN 55905 USA

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 2023年 / 46卷 / 02期

基金：

美国国家科学基金会;

关键词：

Treatment-resistant depression; Children; Adolescents; Major depressive disorder; Antidepressants; Novel treatments; COGNITIVE-BEHAVIORAL THERAPY; MAJOR DEPRESSION; DOUBLE-BLIND; COMPARATIVE EFFICACY; PLACEBO; DISORDER; DESVENLAFAXINE; AUGMENTATION; DEFINITION; SAFETY;

D O I：

10.1016/j.psc.2023.02.007

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

This review highlights existing challenges and the limited evidence base for TRD in chil-dren and adolescents. Although this is a common and impairing condition in childhood, the related research base and clinical guidelines are underdeveloped. As many as 30% of all adolescents treated for depression will have recalcitrant symptoms. Data regarding TRD in children are even more limited. Future work should focus on the un-derlying neurophysiology and related biomarkers. Ideal future staging classifications will have translation utility for both clinical practice and research. Novel intervention development for the population is critical and this research should diverge from the standard approach of adapting adult treatment protocols for children and adolescents.

引用

页码：359 / 370

页数：12

共 64 条

[1] A combined cognitive-behavioral family education intervention for depression in children: A treatment development study [J].

Asarnow, JR ;

Scott, CV ;

Mintz, J .

COGNITIVE THERAPY AND RESEARCH, 2002, 26 (02) :221-229

[2] Desvenlafaxine Versus Placebo in the Treatment of Children and Adolescents with Major Depressive Disorder [J].

Atkinson, Sarah ;

Lubaczewski, Shannon ;

Ramaker, Sara ;

England, Richard D. ;

Wajsbrot, Dalia B. ;

Abbas, Richat ;

Findling, Robert L. .

JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2018, 28 (01) :55-65

[3] Major Depression in the National Comorbidity Survey-Adolescent Supplement: Prevalence, Correlates, and Treatment [J].

Avenevoli, Shelli ;

Swendsen, Joel ;

He, Jian-Ping ;

Burstein, Marcy ;

Merikangas, Kathleen Ries .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2015, 54 (01) :37-44

[4] Practice parameter for the assessment and treatment of children and adolescents with depressive disorders [J].

Birmaher, Boris .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2007, 46 (11) :1503-1526

[5] Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression - The TORDIA randomized controlled trial [J].

Brent, David ;

Emslie, Graham ;

Clarke, Greg ;

Wagner, Karen Dineen ;

Asarnow, Joan Rosenbaum ;

Keller, Marty ;

Vitiello, Benedetto ;

Ritz, Louise ;

Iyengar, Satish ;

Abebe, Kaleab ;

Birmaher, Boris ;

Ryan, Neal ;

Kennard, Betsy ;

Hughes, Carroll ;

DeBar, Lynn ;

McCracken, James ;

Strober, Michael ;

Suddath, Robert ;

Spirito, Anthony ;

Leonard, Henrietta ;

Melhem, Nadine ;

Porta, Giovanna ;

Onorato, Matthew ;

Zelazny, Jamie .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 299 (08) :901-913

[6] Systematic review: Electroconvulsive therapy for treatment-resistant mood disorders in children and adolescents [J].

Castaneda-Ramirez, Santiago ;

Becker, Timothy D. ;

Bruges-Boude, Adriana ;

Kellner, Charles ;

Rice, Timothy R. .

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2023, 32 (09) :1529-1560

[7] Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis [J].

Cipriani, Andrea ;

Zhou, Xinyu ;

Del Giovane, Cinzia ;

Hetrick, Sarah E. ;

Qin, Bin ;

Whittington, Craig ;

Coghill, David ;

Zhang, Yuqing ;

Hazell, Philip ;

Leucht, Stefan ;

Cuijpers, Pim ;

Pu, Juncai ;

Cohen, David ;

Ravindran, Arun V. ;

Liu, Yiyun ;

Michael, Kurt D. ;

Yang, Lining ;

Liu, Lanxiang ;

Xie, Peng .

LANCET, 2016, 388 (10047) :881-890

[8] Left prefrontal transcranial magnetic stimulation for treatment-resistant depression in adolescents: a double-blind, randomized, sham-controlled trial [J].

Croarkin, Paul E. ;

Elmaadawi, Ahmed Z. ;

Aaronson, Scott T. ;

Schrodt, G. Randolph, Jr. ;

Holbert, Richard C. ;

Verdoliva, Sarah ;

Heart, Karen L. ;

Demitrack, Mark A. ;

Strawn, Jeffrey R. .

NEUROPSYCHOPHARMACOLOGY, 2021, 46 (02) :462-469

[9] Predictors and moderators of acute outcome in the Treatment for Adolescents with Depression Study (TADS) [J].

Curry, John ;

Rohde, Paul ;

Simons, Anne ;

Silva, Susan ;

Vitiello, Benedetto ;

Kratochvil, Christopher ;

Reinecke, Mark ;

Feeny, Norah ;

Wells, Karen ;

Pathak, Sanjeev ;

Weller, Elizabeth ;

Rosenberg, David ;

Kennard, Betsy ;

Robins, Michele ;

Ginsburg, Golda ;

March, John .

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2006, 45 (12) :1427-1439

[10] A Double-Blind, Placebo-Controlled Study of Selegiline Transdermal System in Depressed Adolescents [J].

DelBello, Melissa P. ;

Hochadel, Thomas J. ;

Blanchard, Kimberly ;

Azzaro, Albert J. ;

Katic, Alain ;

Khan, Arif ;

Emslie, Graham .

JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2014, 24 (06) :311-317

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