The 5th edition of the World Health Organization Classification of mature lymphoid and stromal tumors - an overview and update

被引：6

作者：

Attygalle, Ayoma D. ^{[1
]}

Chan, John K. C. ^{[2
]}

Coupland, Sarah E. ^{[3
,4
]}

Du, Ming-Qing ^{[5
]}

Ferry, Judith A. ^{[6
,7
]}

de Jong, Daphne ^{[8
]}

Gratzinger, Dita ^{[9
]}

Lim, Megan S. ^{[10
]}

Naresh, Kikkeri N. ^{[11
]}

Nicolae, Alina ^{[12
]}

Ott, German ^{[13
,14
]}

Rosenwald, Andreas ^{[15
,16
]}

Schuh, Anna ^{[17
]}

Siebert, Reiner ^{[18
,19
]}

机构：

[1] Royal Marsden Hosp, Dept Histopathol, London, England

[2] Queen Elizabeth Hosp, Dept Pathol, kowloon, Hong Kong, Peoples R China

[3] Univ Liverpool, Dept Mol & Clin Canc Med, ISMIB, Liverpool, Merseyside, England

[4] Liverpool Univ Hosp Fdn Trust, Liverpool Clin Labs, Liverpool, Merseyside, England

[5] Univ Cambridge, Dept Pathol, Cambridge, England

[6] Massachusetts Gen Hosp, Dept Pathol, Boston, MA USA

[7] Harvard Med Sch, Boston, MA USA

[8] Netherlands Canc Inst, Amsterdam, Netherlands

[9] Stanford Univ, Sch Med, Dept Pathol, Stanford, CA USA

[10] Mem Sloan Kettering Canc Ctr, New York, NY USA

[11] Univ Washington, Fred Hutchinson Canc Ctr, Seattle, WA USA

[12] Univ Hosp Strasbourg, Dept Pathol, Strasbourg, France

[13] Robert Bosch Krankenhaus, Dept Clin Pathol, Stuttgart, Germany

[14] Dr Margarete Fischer Bosch Inst Clin Pharmacol, Stuttgart, Germany

[15] Julius Maximilians Univ Wurzburg, Inst Pathol, Wurzburg, Germany

[16] Canc Ctr Mainfranken, Wurzburg, Germany

[17] Univ Oxford, Dept Oncol, Oxford, England

[18] Univ Ulm, Inst Human Genet, Ulm, Germany

[19] Ulm Univ, Med Ctr, Ulm, Germany

来源：

LEUKEMIA & LYMPHOMA | 2024年 / 65卷 / 04期

关键词：

WHO-HAEM5; modification of nomenclature; refinement of diagnostic criteria; B-CELL LYMPHOMA; PREDOMINANT HODGKIN LYMPHOMA; IMMUNOGLOBULIN DEPOSITION DISEASE; FOLLICULAR DENDRITIC CELLS; EFFUSION-BASED LYMPHOMA; GENOME-WIDE ANALYSIS; GRAY ZONE LYMPHOMA; LYMPHOPROLIFERATIVE DISEASE; WALDENSTROM MACROGLOBULINEMIA; MUTATIONAL LANDSCAPE;

D O I：

10.1080/10428194.2023.2297939

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The purpose of this review is to give an overview on the conceptual framework and major developments of the upcoming 5th edition of the World Health Organization (WHO) Classification of Haematolymphoid tumours (WHO-HAEM5) and to highlight the most significant changes made in WHO-HAEM5 compared with the revised 4th edition (WHO-HAEM4R) of lymphoid and stromal neoplasms. The changes from the revised 4th edition include the reorganization of entities by means of a hierarchical system that is realized throughout the 5th edition of the WHO classification of tumors of all organ systems, a modification of nomenclature for some entities, the refinement of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities. For the first time, tumor-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms are included in the classification.

引用

页码：413 / 429

页数：17

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