Removal and recovery of deep eutectic solvent with membrane-based methodology: A promising strategy to enhance extraction and purification of Dendrobium officinale flavonoids

被引：12
作者：
Sui, Minghui [1 ]
Feng, Simin [1 ]
Yu, Jiahao [1 ]
Chen, Bilian [3 ]
Li, Zhenhao [4 ]
Shao, Ping [1 ,2 ]
机构：
[1] Zhejiang Univ Technol, Dept Food Sci & Technol, Hangzhou 310014, Zhejiang, Peoples R China
[2] Ecoind Innovat Inst ZJUT, Quzhou 324000, Zhejiang, Peoples R China
[3] Zhejiang Inst Food & Drug Control, Hangzhou 310052, Zhejiang, Peoples R China
[4] Zhejiang ShouXiangu Bot Drug Inst Co LTD, Hangzhou 321200, Zhejiang, Peoples R China
来源：
INDUSTRIAL CROPS AND PRODUCTS | 2023年 / 206卷
基金：
中国国家自然科学基金;
关键词：
Dendrobium officinale; Flavonoids; Deep eutectic solvent; Electrodialysis; Ultrafiltration; UPLC-Triple-TOF/MS; POLYSACCHARIDES; SEPARATION;
D O I：
10.1016/j.indcrop.2023.117638
中图分类号：
S2 [农业工程];
学科分类号：
0828 ;
摘要：
Finding efficient, environmental friendly extraction and purification methods of natural active substances has always been a research hotspot in the field of food. In this study, the yield (36.76 +/- 2.17 mg/g) of Dendrobium officinale flavonoids (DOFs) was significantly increased by ultrasonic-assisted deep eutectic solvent (DES) method. DES was removed and recovered from the Dendrobium officinale extracts by bipolar membrane elec-trodialysis (BME). At 70 V, the removal ratios of choline chloride (ChCl) and lactic acid (Lac) could reach 92 % and 90 %, and DOFs were further enriched. Then, Dendrobium officinale polysaccharides (DOPs) was effectively separated from DOFs component using ultrafiltration (UF). After BME-UF treatment, the purification efficiency of DOFs by macroporous resin (MR) was increased by 2.1 times. UPLC-Triple-TOF/MS results further confirmed that, the content of DOFs was increased by 59 times after purification. This study suggested that BME-UF was a valid method for purification of flavonoids, which also promoted green extraction.
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页数：12
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