Counting statistics based on the analytic solutions of the differential-difference equation for birth-death processes

被引:2
作者
Park, Seong Jun [1 ,2 ,3 ]
Choi, M. Y. [2 ,3 ]
机构
[1] Chung Ang Univ, Natl CRI Ctr Chem Dynam Living Cells, Seoul 06974, South Korea
[2] Seoul Natl Univ, Dept Phys & Astron, Seoul 08826, South Korea
[3] Seoul Natl Univ, Ctr Theoret Phys, Seoul 08826, South Korea
基金
新加坡国家研究基金会;
关键词
Counting statistics; Birth-death process; Differential-difference equation; Rate fluctuations; Master equation; CANCER;
D O I
10.1016/j.chaos.2023.113679
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
Birth-death processes take place ubiquitously throughout the universe. In general, birth and death rates depend on the system size (corresponding to the number of products or customers undergoing the birth-death process) and thus vary every time birth or death occurs, which makes fluctuations in the rates inevitable. The differentialdifference equation governing the time evolution of such a birth-death process is well established, but it resists solving for a non-asymptotic solution. In this work, we present the analytic solution of the differential-difference equation for birth-death processes without approximation. The time-dependent solution we obtain leads to an analytical expression for counting statistics of products (or customers). We further examine the relationship between the system size fluctuations and the birth and death rates, and find that statistical properties (variance subtracted by mean) of the system size are determined by the mean death rate as well as the covariance of the system size and the net growth rate (i.e., the birth rate minus the death rate). This work suggests a promising new direction for quantitative investigations into birth-death processes.
引用
收藏
页数:6
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